Power-efficient self-cleaning hydrophilic condenser surface for portable exhaled breath condensate (EBC) metabolomic sampling

Journal of Breath Research
Konstantin O ZamuruyevCristina E Davis

Abstract

In this work, we present a hydrophilic self-cleaning condenser surface for the collection of biological and environmental aerosol samples. The condenser is installed in a battery-operated hand-held breath sampling device. The device performance is characterized by the collection and analysis of exhaled breath samples from a group of volunteers. The exhaled breath condensate is collected on a subcooled condenser surface, transferred into a storage vial, and its chemical content is analyzed using mass spectrometric methods. The engineered surface supports upon it a continuous condensation cycle, and this allows the collection of liquid samples exceeding the saturation mass/area limit of a plain hydrophilic surface. The condenser surface employs two constituent parameters: a low surface energy barrier to enhance nucleation and condensation efficiency, and a network of surface microstructures to create a self-cleaning mechanism for fluid aggregation into a reservoir. Removal of the liquid condensate from the condenser surface prevents the formation of a thick liquid layer, and thus maintains a continuous condensation cycle with a minimum decrease in heat transfer efficiency as condensation occurs on the surface. The self-cleaning c...Continue Reading

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Jul 18, 2018·Analytica Chimica Acta·Konstantin O ZamuruyevCristina E Davis

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Citations

Jul 26, 2019·Journal of Breath Research·Alexander J SchmidtCristina E Davis
Mar 11, 2021·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Eva BorrasEdward S Schelegle
Sep 4, 2021·Expert Review of Proteomics·Natalia ZakharovaAlexey S Kononikhin

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