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Powerful SNP-set analysis for case-control genome-wide association studies

American Journal of Human Genetics

Jun 22, 2010

Michael C WuXihong Lin

Abstract

GWAS have emerged as popular tools for identifying genetic variants that are associated with disease risk. Standard analysis of a case-control GWAS involves assessing the association between each individual genotyped SNP and disease risk. However, this approach suffers from limited repr...read more

Mentioned in this Paper

Genome-Wide Association Study
Biochemical Pathway
SLC38A1 gene
Genome
NAT2 protein, human
FGFR2 gene
Fibroblast Growth Factor Receptor 2
ASAH1 gene
NAT2 gene
Genetic Markers
393
1
Paper Details
References
  • References37
  • Citations235
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  • References37
  • Citations235
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Powerful SNP-set analysis for case-control genome-wide association studies

American Journal of Human Genetics

Jun 22, 2010

Michael C WuXihong Lin

PMID: 20560208

DOI: 10.1016/j.ajhg.2010.05.002

Abstract

GWAS have emerged as popular tools for identifying genetic variants that are associated with disease risk. Standard analysis of a case-control GWAS involves assessing the association between each individual genotyped SNP and disease risk. However, this approach suffers from limited repr...read more

Mentioned in this Paper

Genome-Wide Association Study
Biochemical Pathway
SLC38A1 gene
Genome
NAT2 protein, human
FGFR2 gene
Fibroblast Growth Factor Receptor 2
ASAH1 gene
NAT2 gene
Genetic Markers
393
1

Feeds With Similar Papers

Hormone-Related Cancers

This feed focuses on hormone-related cancers including cancer of the breast, endometrium, ovary, prostate, testis, thyroid, and bone, all of which share unique mechanisms of carcinogenesis. Here is the latest research.

Human Cell Atlas Consortium

The aim of the Human Cell Atlas is to build reference maps of all human cells in order to enhance our understanding of health and disease. Follow the latest research from the Human Cell Atlas Consortium here.

Related Papers

American Journal of Human Genetics

A powerful and flexible multilocus association test for quantitative traits

American Journal of Human GeneticsFebruary 7, 2008
Lydia Coulter KweeMichael P Epstein
American Journal of Human Genetics

Rare-variant association testing for sequencing data with the sequence kernel association test

American Journal of Human GeneticsJuly 9, 2011
Michael C WuXihong Lin
Paper Details
References
  • References37
  • Citations235
1234
  • References37
  • Citations235
12345...

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