PMID: 2110550May 15, 1990Paper

pp60c-src protein kinase activity in human gastric carcinomas

International Journal of Cancer. Journal International Du Cancer
N TakekuraE Tahara

Abstract

We examined pp60c-src protein kinase activity in human gastric carcinoma cell lines and gastric carcinoma tissues as well as normal mucosa. pp60c-src kinase activity was detected in all 5 carcinoma cell lines at various levels. Of 16 gastric carcinoma tissues, 8 showed higher pp60c-src kinase activity in tumor tissues than in corresponding normal mucosa. However, the levels of expression of pp60c-src detected by Western blotting were not always consistent with the activities of pp60c-src protein kinase. These findings suggest that the increase in pp60c-src protein kinase activity might be brought about by post-translational changes.

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May 29, 2013·Cancer Chemotherapy and Pharmacology·Min ShiJun Zhang
Feb 27, 2001·Annals of Surgery·B P WijnhovenW N Dinjens
Mar 14, 2007·Anti-cancer Drugs·Ami N Shah, Gary E Gallick
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Jan 31, 2002·World Journal of Gastroenterology : WJG·Xiu-Jie WangChao-Jun Wang
Oct 1, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·George D DemetriT R Jeffry Evans
Dec 10, 2020·International Journal of Molecular Sciences·Kyoung-Min ChoiJae-Young Kim

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