Practical and clinical considerations in Cobalt-60 tomotherapy.

Journal of Medical Physics
Chandra P JoshiL John Schreiner

Abstract

Cobalt-60 (Co-60) based radiation therapy continues to play a significant role in not only developing countries, where access to radiation therapy is extremely limited, but also in industrialized countries. Howver, technology has to be developed to accommodate modern techniques, including image guided and adaptive radiation therapy (IGART). In this paper we describe some of the practical and clinical considerations for Co-60 based tomotherapy by comparing Co-60 and 6 MV linac-based tomotherapy plans for a head and neck (HandN) cancer and a prostate cancer case. The tomotherapy IMRT plans were obtained by modeling a MIMiC binary multi-leaf collimator attached to a Theratron-780c Co-60 unit and a 6 MV linear accelerator (CL2100EX). The EGSnrc/BEAMnrc Monte Carlo (MC) code was used for the modeling of the treatment units with the MIMiC collimator and EGSnrc/DOSXYZnrc code was used for beamlet dose data. An in-house inverse treatment planning program was then used to generate optimized tomotherapy dose distributions for the H and N and prostate cases. The dose distributions, cumulative dose area histograms (DAHs) and dose difference maps were used to evaluate and compare Co-60 and 6 MV based tomotherapy plans. A quantitative analys...Continue Reading

References

May 1, 1995·Medical Physics·D W RogersT R Mackie
Feb 13, 2001·International Journal of Radiation Oncology, Biology, Physics·P van der Giessen
Jun 23, 2006·Physics in Medicine and Biology·T R Mackie
Nov 8, 2007·Medical Physics·Pat Cadman
Jan 18, 2008·Physics in Medicine and Biology·Chandra P JoshiL John Schreiner

❮ Previous
Next ❯

Citations

Aug 10, 2013·Medical Physics·Sandeep DhanesarL John Schreiner
Apr 2, 2011·Medical Physics·Patrick Cadman, Karl Bzdusek
Jan 13, 2016·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Catherine MernaPercy Lee
Mar 12, 2015·International Journal of Radiation Biology·José Fernando Bastos MouraRonaldo Albuquerque Ribeiro
Jun 25, 2015·International Journal of Radiation Oncology, Biology, Physics·H Omar WootenSasa Mutic
May 3, 2016·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·J-B KamanziG Noël
Jun 28, 2011·Plastic and Reconstructive Surgery·Catherine N Tchanque-FossuoSteven R Buchman

❮ Previous
Next ❯

Methods Mentioned

BETA
Hi-Art

Software Mentioned

BEAMnrc
DOSXYZnrc

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.