Practical considerations of linear accelerator-based frameless extracranial radiosurgery for treatment of occipital neuralgia for nonsurgical candidates

Journal of Applied Clinical Medical Physics
Travis R DentonAaron C Spalding

Abstract

Occipital neuralgia generally responds to medical or invasive procedures. Repeated invasive procedures generate increasing complications and are often contraindicated. Stereotactic radiosurgery (SRS) has not been reported as a treatment option largely due to the extracranial nature of the target as opposed to the similar, more established trigeminal neuralgia. A dedicated phantom study was conducted to determine the optimum imaging studies, fusion matrices, and treatment planning parameters to target the C2 dorsal root ganglion which forms the occipital nerve. The conditions created from the phantom were applied to a patient with medically and surgically refractory occipital neuralgia. A dose of 80 Gy in one fraction was prescribed to the C2 occipital dorsal root ganglion. The phantom study resulted in a treatment achieved with an average translational magnitude of correction of 1.35 mm with an acceptable tolerance of 0.5 mm and an average rotational magnitude of correction of 0.4° with an acceptable tolerance of 1.0°. For the patient, the spinal cord was 12.0 mm at its closest distance to the isocenter and received a maximum dose of 3.36 Gy, a dose to 0.35 cc of 1.84 Gy, and a dose to 1.2 cc of 0.79 Gy. The brain maximum dose ...Continue Reading

References

Jan 1, 1992·Clinical Neurology and Neurosurgery·M Anthony
Jan 1, 1982·Applied Neurophysiology·H BlumeC Rojas
Jan 1, 1994·Acta neurochirurgica·M T Stechison, B B Mullin
May 13, 1999·The British Journal of Radiology·S C LillicrapA J O'Connor
Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·C L RogersB L Speiser
Feb 13, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·L GilbeauV Grégoire
Jul 20, 2001·British Journal of Anaesthesia·T J Nurmikko, P R Eldridge
May 22, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Dirk VerellenGuy Storme
Jun 18, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·B C LopezJ M Zakrzewska
Mar 9, 2005·Journal of Applied Clinical Medical Physics·Bruce J GerbiWalter A Hall
Jun 1, 2005·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·G C Manzoni, P Torelli
Jun 24, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Peter J WersällChrister Svedman
Jul 27, 2006·Technology in Cancer Research & Treatment·Pantaleo RomanelliJohn R Adler
Sep 19, 2006·The British Journal of Radiology·M L Kessler
Apr 21, 2007·International Journal of Radiation Oncology, Biology, Physics·Rob H IrelandMartin H Robinson
Dec 18, 2007·Neurosurgical Focus·Gerhard M FriehsPrakash Sampath
Feb 26, 2008·Medical Physics·Indra J DasAnders Ahnesjö
Apr 4, 2008·Medical Physics·Paolo FrancesconCarlo Cavedon
Dec 1, 2006·Journal of Neurosurgery·Ian Paddick, Bodo Lippitz
Dec 17, 2008·International Journal of Radiation Oncology, Biology, Physics·Martin J Murphy
Aug 4, 2009·Technology in Cancer Research & Treatment·Arjun SahgalMichael Schwartz
Oct 9, 2009·Medical Physics·Eric E KleinUNKNOWN Task Group 142, American Association of Physicists in Medicine
Jan 13, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Inga S GrillsLarry L Kestin
Oct 1, 2010·Medical Physics·Stanley H BenedictFang-Fang Yin
Apr 12, 2011·International Journal of Radiation Oncology, Biology, Physics·Thierry GevaertMark De Ridder
Jul 12, 2011·Journal of Neurosurgery·Bruce E Pollock, Christopher J Boes
Aug 6, 2011·Medical Physics·Sonja DieterichCheng Yu
Nov 18, 2011·Journal of Applied Clinical Medical Physics·Pejman RowshanfarzadPeter B Greer
Jan 11, 2012·Journal of Applied Clinical Medical Physics·Gocha KhelashviliJulius Turian
May 16, 2012·Journal of Applied Clinical Medical Physics·Jinkoo KimSamuel Ryu
Jun 9, 2012·Stereotactic and Functional Neurosurgery·Sinisa StanicRobin L Stern
Sep 8, 2012·Journal of Applied Clinical Medical Physics·David S FollowillGeoffrey S Ibbott
Nov 15, 2012·Journal of Applied Clinical Medical Physics·Anees DhabaanHui-Kuo Shu
Dec 13, 2012·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·F A ZeilerM West
Apr 17, 2014·Current Pain and Headache Reports·Carrie Dougherty
Sep 23, 2014·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Alper CesmebasiMarios Loukas
Dec 2, 2014·Journal of Neurosurgery·Roberto Martínez-ÁlvarezGermán Rey-Portolés
Jun 24, 2015·Journal of Applied Clinical Medical Physics·Travis R DentonAaron C Spalding

❮ Previous
Next ❯

Citations

Mar 5, 2019·Current Pain and Headache Reports·Alaa Abd-ElsayedKenneth Fiala
Sep 10, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Enrique Martínez-PíasÁngel Luis Guerrero Peral
Sep 21, 2021·Acta Neurologica Scandinavica·Isabela Maria Garcia MarcollaHélio A Ghizoni Teive

❮ Previous
Next ❯

Methods Mentioned

BETA
IEC

Software Mentioned

SRS
ExacTrac
Novalis

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.