Practical considerations on current guidelines for the management of non-neutropenic adult patients with candidaemia

Mycoses
Andreas Glöckner, O A Cornely

Abstract

Recent guideline recommendations on the management of candidaemia provide valuable treatment guidance for routine clinical practice, but need to be interpreted in the light of the actual situation of the patient and the local epidemiology of fungal infections. Echinocandins emerge as the generally preferred primary treatment. Treatment should be initiated immediately after notification of a Candida-positive blood culture in all patients. Ambiguous issues include the definition of optimum duration of treatment, the indication and time point to step down to oral azoles, catheter management, and the appropriate approach in critically ill patients at high risk for candidaemia in the absence of definitive proof of infection. Patients with clinical suspicion of antifungal treatment failure need prompt workup for adequacy of treatment, focal sources of sustained infection and potential superinfection.

References

Dec 1, 1988·Archives of Internal Medicine·S B WeyR P Wenzel
Mar 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J K Stamos, A H Rowley
Oct 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J H RexR G Washburn
Jul 24, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M NucciW Pulcheri
May 17, 2002·The Journal of Hospital Infection·V Krcmery, A J Barnes
Nov 13, 2002·The American Journal of Medicine·Stijn I BlotFrancis A Colardyn
Dec 20, 2002·The New England Journal of Medicine·Jorge Mora-DuarteUNKNOWN Caspofungin Invasive Candidiasis Study Group
Jul 29, 2003·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A L ColomboN Kartsonis
Oct 15, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Olafur GudlaugssonDaniel Diekema
Apr 16, 2004·Clinical Microbiology Reviews·Erna M Kojic, Rabih O Darouiche
Aug 13, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Hilmar WisplinghoffMichael B Edmond
Mar 15, 2005·Scandinavian Journal of Infectious Diseases·Lena Rós AsmundsdóttirMagnús Gottfredsson
Apr 5, 2005·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·I SteinerP G E Kennedy
Oct 6, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Theoklis E ZaoutisChris Feudtner
Jun 8, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kevin W GareyDavid T Bearden
Jun 15, 2007·The New England Journal of Medicine·Annette C ReboliUNKNOWN Anidulafungin Study Group
Jul 6, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D RodriguezUNKNOWN Barcelona Candidemia Project Study Group
Aug 31, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F DrobniewskiUNKNOWN Subcommittee on Antimicrobial Susceptibility Testing of Mycobacterium tuberculosis of the European Committee for Antimicrobi
Sep 7, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter G PappasDonald N Buell
Jun 13, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E Velasco, R Bigni
Oct 1, 2008·Critical Care Medicine·Andrew J LabelleMarin H Kollef
Dec 11, 2008·Intensive Care Medicine·Sean M BagshawUNKNOWN Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group
Feb 5, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter G PappasUNKNOWN Infectious Diseases Society of America
Jun 18, 2009·American Journal of Therapeutics·Gourang P PatelNimish Patel
Sep 30, 2009·Antimicrobial Agents and Chemotherapy·Paul A MannTodd A Black
Nov 4, 2009·Antimicrobial Agents and Chemotherapy·Ying TaurSusan K Seo
Mar 30, 2010·FEMS Yeast Research·Marc SeidlerFrank-Michael C Müller
Jun 29, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marcio NucciOlivier Lortholary
Jul 28, 2010·Bone Marrow Transplantation·J MaertensUNKNOWN Third European Conference on Infections in Leukemia
Nov 17, 2010·Antimicrobial Agents and Chemotherapy·Olivier LortholaryUNKNOWN French Mycosis Study Group
Mar 1, 2011·Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy·M A PfallerUNKNOWN CLSI Subcommittee for Antifungal Testing
Jun 15, 2011·Journal of Microbiological Methods·D EstivillM P Arévalo
Jul 28, 2011·Current Infectious Disease Reports·Nicolas AllouPhilippe Montravers
Aug 4, 2011·Journal of Clinical Medicine Research·Jorge A GuzmanJack D Sobel
Jan 4, 2012·The American Journal of Medicine·Michael A Pfaller

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Citations

Aug 6, 2014·Intensive Care Medicine·Danièle MaubonMuriel Cornet
Apr 10, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A FekkarA Datry
Nov 11, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S AriasF Zech
Aug 16, 2014·Bioorganic & Medicinal Chemistry·Gregory L BackesBranko S Jursic
Jul 12, 2016·The Cochrane Database of Systematic Reviews·Susanne Janum, Arash Afshari
Jan 30, 2014·International Reviews of Immunology·Tiffany CazaAndras Perl
Jun 28, 2018·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Sibylle C MellinghoffOliver A Cornely

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