Practical guidance for the management of iron deficiency in patients with inflammatory bowel disease

Therapeutic Advances in Gastroenterology
Dorothea NiepelJan Wehkamp

Abstract

Iron deficiency or iron deficiency anemia (IDA) are some of the most common systemic complications of inflammatory bowel diseases (IBD). Symptoms such as fatigue, reduced ability to concentrate and reduced exercise tolerance can mimic common symptoms of IBD and can therefore easily be overseen. Furthermore, clinicians tend to see mild to moderate anemia as an inevitable accompaniment of IBD that is sufficiently explained by the underlying disease and does not require further workup. But in contrast to these clinical routines, current guidelines recommend that any degree of anemia in patients with IBD should be further evaluated and treated. Multiple studies have shown that anemia is a main factor for decreased quality of life (QoL) in patients with IBD. Correction of anemia, however, can significantly improve the QoL of patients with IBD. It is therefore recommended that every patient with IBD is regularly screened for iron deficiency and anemia. If detected, appropriate workup and treatment should be initiated. Over the last years, a number of new diagnostic tools and treatment options have been developed. Multiple studies have demonstrated the safety of newer formulations of intravenous iron in patients with IBD and have comp...Continue Reading

References

Mar 7, 1996·The New England Journal of Medicine·S SchreiberA Raedler
Aug 22, 2001·The American Journal of Gastroenterology·C C Cronin, F Shanahan
Aug 22, 2001·The American Journal of Gastroenterology·C GascheUNKNOWN Austrian Inflammatory Bowel Diseases Study Group
Feb 19, 2003·Clinica Chimica Acta; International Journal of Clinical Chemistry·Yves Beguin
Apr 29, 2004·American Journal of Hematology·Scott B Silverstein, George M Rodgers
May 20, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Glenn M ChertowJarl Ahlmén
Jul 13, 2004·Gut·C GascheG Weiss
Aug 11, 2004·The Journal of Pharmacology and Experimental Therapeutics·Salvatore CuzzocreaChristoph Thiemermann
Mar 11, 2005·The New England Journal of Medicine·Guenter Weiss, Lawrence T Goodnough
Sep 17, 2005·Scandinavian Journal of Gastroenterology·Kari ErichsenTrygve Hausken
Nov 16, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Glenn M ChertowJarl Ahlmén
Jan 9, 2007·Alimentary Pharmacology & Therapeutics·S Kulnigg, C Gasche
May 8, 2007·Lancet·Michael AuerbachJohn Glaspy
Sep 11, 2007·World Journal of Gastroenterology : WJG·Georgia Tsiolakidou, Ioannis-E Koutroubakis
Nov 7, 2007·Inflammatory Bowel Diseases·Christoph GascheGert Van Assche
May 15, 2008·The American Journal of Gastroenterology·Javier P Gisbert, Fernando Gomollón
Aug 22, 2008·Digestive Diseases and Sciences·Basak CakalHandan Ankarali
Jun 6, 2009·The American Journal of Gastroenterology·Stefanie KulniggChristoph Gasche
Sep 30, 2009·World Journal of Gastroenterology : WJG·Manuel MuñozJosé Antonio García-Erce
Sep 30, 2009·World Journal of Gastroenterology : WJG·Rosario Moreno LópezFernando Gomollón García
Jan 8, 2010·The New England Journal of Medicine·Ellis F UngerRobert Temple
Oct 7, 2010·Nature Reviews. Gastroenterology & Hepatology·Jürgen SteinAxel U Dignass
Oct 22, 2010·The American Journal of Clinical Nutrition·Michael B ZimmermannRichard F Hurrell
Dec 1, 2007·Journal of Crohn's & Colitis·Konstantinos KatsanosGert Van Assche
Dec 24, 2010·Journal of Clinical Pathology·Manuel MuñozÁngel Francisco Remacha
Jan 18, 2011·Hematology·Michael Auerbach, Harold Ballard
Oct 20, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Rayko EvstatievUNKNOWN FERGI Study Group
Oct 9, 2013·European Journal of Gastroenterology & Hepatology·Jürgen SteinSilvio Danese
Dec 18, 2014·Journal of Crohn's & Colitis·Axel U DignassUNKNOWN European Crohn’s and Colitis Organisation [ECCO]
Sep 1, 2015·Lancet·Anthony LopezLaurent Peyrin-Biroulet

❮ Previous
Next ❯

Citations

Nov 18, 2020·Nutrients·Aditi Kumar, Matthew J Brookes
Jan 21, 2021·The Cochrane Database of Systematic Reviews·Morris GordonAnthony K Akobeng
Feb 4, 2021·Nutrients·Giulio VernaPietro Campiglia
Mar 12, 2021·Expert Review of Gastroenterology & Hepatology·Yash ShahNabeel Khan
Jul 22, 2021·International Journal of Laboratory Hematology·Nicola SvensonNina Dempsey-Hibbert
Aug 28, 2021·Nutrients·Georgiana-Emmanuela Gîlcă-BlanariuGabriela Ștefănescu
Aug 11, 2020·GE Portuguese Journal of Gastroenterology·Ana Isabel LopesHenedina Antunes

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Related Papers

World Journal of Gastroenterology : WJG
Winfried HäuserAntonina Mikocka-Walus
The American Journal of Gastroenterology
Benjamin A GoldenbergCharles N Bernstein
Current Opinion in Gastroenterology
Fernando Gomollón, Javier P Gisbert
© 2022 Meta ULC. All rights reserved