Practical Guide to the Identification and Diagnosis of Asthma-COPD Overlap (ACO)

COPD
Alexa NuñezMiriam Barrecheguren

Abstract

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of mortality around the world. COPD is characterised by a heterogeneous clinical presentation and prognosis which may vary according to the clinical phenotype. One of the phenotypes of COPD most frequently studied is the asthma-COPD overlap (ACO), however, there are no universally accepted diagnostic criteria for ACO. It is recognised that the term ACO includes patients with clinical features of both asthma and COPD, such as more intense eosinophilic bronchial inflammation, more severe respiratory symptoms and more frequent exacerbations, but in contrast, it is associated with a better prognosis compared to COPD. More importantly, ACO patients show better response to inhaled corticosteroid treatment than other COPD phenotypes. The diagnosis of ACO can be difficult in clinical practice, and the identification of these patients can be a challenge for non-specialized physicians. We describe how to recognise and diagnose ACO based on a recently proposed Spanish algorithm and by the analysis of three clinical cases of patients with COPD. The diagnosis of ACO is based on the diagnosis of COPD (chronic airflow obstruction in an adult with significant smoking exp...Continue Reading

References

Nov 9, 2000·American Journal of Respiratory and Critical Care Medicine·A PapiL M Fabbri
Feb 8, 2008·The European Respiratory Journal·D P TashkinS Kesten
Sep 29, 2011·Respiratory Research·Megan HardinUNKNOWN COPDGene Investigators
Feb 9, 2012·Lancet·Marc DecramerMarc Miravitlles
Mar 12, 2013·Expert Review of Clinical Pharmacology·Samuel LouieTimothy E Albertson
Apr 20, 2013·Respiratory Medicine·Marc MiravitllesFrancisco García-Río
Jun 5, 2013·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Vladimir KoblizekUNKNOWN Czech Pneumological and Phthisiological Society
Jun 17, 2014·Respiratory Medicine·José M MarínMarc Miravitlles
Nov 19, 2014·Current Opinion in Pulmonary Medicine·Miriam BarrechegurenMarc Miravitlles
Dec 18, 2014·Basic & Clinical Pharmacology & Toxicology·Hannu KankaanrantaLauri Lehtimäki
Jan 23, 2015·American Journal of Respiratory and Critical Care Medicine·Stephanie A ChristensonPrescott G Woodruff
Aug 21, 2015·Chest·Borja G CosioUNKNOWN CHAIN Study
Dec 19, 2015·Archivos de bronconeumología·Miriam BarrechegurenMarc Miravitlles
Dec 29, 2015·Archivos de bronconeumología·Vicente Plaza Moral, UNKNOWN Comité Ejecutivo de GEMA
Mar 13, 2016·Therapeutic Advances in Respiratory Disease·María del Carmen García-GarcíaMarc Miravitlles
Mar 19, 2016·The European Respiratory Journal·Keele E WurstJørgen Vestbo
May 26, 2016·American Journal of Respiratory and Critical Care Medicine·Masaru SuzukiUNKNOWN Hokkaido COPD cohort study investigators
Jun 9, 2016·Annals of the American Thoracic Society·James CosentinoUNKNOWN COPDGene Investigators
Jun 25, 2016·The European Respiratory Journal·Don D SinMichael E Wechsler
Nov 11, 2016·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Cleriston Farias QueirozEdgar Marcelino de Carvalho
May 4, 2017·The European Respiratory Journal·Minna TommolaHannu Kankaanranta
May 4, 2017·The European Respiratory Journal·Borja G CosíoUNKNOWN on behalf of the CHACOS study group
May 4, 2017·The European Respiratory Journal·Marc MiravitllesVicente Plaza
May 4, 2017·The European Respiratory Journal·Marc Miravitlles
Feb 28, 2018·International Journal of Chronic Obstructive Pulmonary Disease·Luis Pérez de LlanoIrina Bobolea
Oct 31, 2018·Respiratory Research·Lystra P HaydenUNKNOWN COPDGene Investigators
Nov 15, 2018·International Journal of Chronic Obstructive Pulmonary Disease·Zuzana DiamantRichard E Russell

❮ Previous
Next ❯

Citations

Apr 14, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Alexa NuñezMiriam Barrecheguren
Feb 18, 2020·Archivos de bronconeumología·Marc MiravitllesBernardino Alcázar
Oct 3, 2020·Archivos de bronconeumología·Mònica MonteagudoMarc Miravitlles
Nov 14, 2020·The Journal of Allergy and Clinical Immunology. in Practice·So-Young ParkUNKNOWN Cohort for Reality and Evolution of Adult Asthma in Korea (COREA) Study Group
Mar 24, 2021·NPJ Primary Care Respiratory Medicine·Mònica MonteagudoMarc Miravitlles
May 21, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Ioanna TsiligianniRudi Peché
Jun 26, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Evgeni MekovMarc Miravitlles
Dec 1, 2019·Archivos de bronconeumología·Juan José Soler-CataluñaMarc Miravitlles

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

The Journal of Allergy and Clinical Immunology. in Practice
Stephen MilneDon D Sin
Allergology International : Official Journal of the Japanese Society of Allergology
Akifumi UchidaHiromasa Inoue
The Journal of Asthma : Official Journal of the Association for the Care of Asthma
Linda EkerljungJan Lötvall
© 2022 Meta ULC. All rights reserved