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Practical kinetics III: benzodiazepine hydrolysis

Journal of Pharmaceutical Sciences

Feb 1, 1975

H V MauldingA F Michaelis

PMID: 236375

Abstract

The velocity constants for chlordiazepoxide hydrolysis were measured by independent techniques. A quantitative TLC kinetic procedure is compared with an extractive method. The data derived from both processes are in approximate agreement, further exemplifying the feasibility of TLC for ...read more

Mentioned in this Paper

Benzophenone
Phosphate buffers
Methylamine
Cytokinesis of the Fertilized Ovum
Benzodiazepine [EPC]
Ampholytes
Formates
Spectrophotometry, Ultraviolet
Catalysis
Cytokinesis
Paper Details
References
  • References1
  • Citations6
1
  • References1
  • Citations6
1

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Practical kinetics III: benzodiazepine hydrolysis

Journal of Pharmaceutical Sciences

Feb 1, 1975

H V MauldingA F Michaelis

PMID: 236375

DOI:

Abstract

The velocity constants for chlordiazepoxide hydrolysis were measured by independent techniques. A quantitative TLC kinetic procedure is compared with an extractive method. The data derived from both processes are in approximate agreement, further exemplifying the feasibility of TLC for ...read more

Mentioned in this Paper

Benzophenone
Phosphate buffers
Methylamine
Cytokinesis of the Fertilized Ovum
Benzodiazepine [EPC]
Ampholytes
Formates
Spectrophotometry, Ultraviolet
Catalysis
Cytokinesis

Related Papers

Journal of Pharmaceutical Sciences

Kinetics and mechanisms of hydrolysis of 1,4-benzodiazepines I: chlordiazepoxide and demoxepam

Journal of Pharmaceutical SciencesAugust 1, 1976
W W HanD D Maness
Journal of Pharmaceutical Sciences

Kinetics and mechanisms of hydrolysis of 1,4-benzodiazepines III: nitrazepam

Journal of Pharmaceutical SciencesJune 1, 1977
W W HanD D Maness
Paper Details
References
  • References1
  • Citations6
1
  • References1
  • Citations6
1
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