Practical recommendations for the choice of anticoagulants in the management of patients with atrial fibrillation on ibrutinib

Leukemia & Lymphoma
Khai Li ChaiConstantine S Tam

Abstract

The management of AF represents a major challenge in patients with CLL, especially in elderly patients with multiple comorbidities who are representative of the majority of patients with CLL. This is especially complex in the case of ibrutinib. Many anticoagulants have potential for pharmacological interaction with ibrutinib, and ibrutinib itself has antiplatelet properties. Use of ibrutinib therapy in these patients mandates review and revision of the need for anticoagulation and best anticoagulant to use. Herein, we review the current knowledge of the metabolism of common anticoagulants and how they may interact with ibrutinib.

References

Jul 11, 2003·The New England Journal of Medicine·Agnes Y Y LeeUNKNOWN Randomized Comparison of Low-Molecular-Weight Heparin versus Oral Anticoagulant Therapy for the Prevention of Recurrent Veno
Apr 30, 2013·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Hein HeidbuchelUNKNOWN European Heart Rhythm Association
Jun 21, 2013·The New England Journal of Medicine·Michael L WangKristie A Blum
Dec 8, 2015·The New England Journal of Medicine·Jan A BurgerUNKNOWN RESONATE-2 Investigators
Nov 26, 2016·Leukemia & Lymphoma·Tait D ShanafeltNeil E Kay

❮ Previous
Next ❯

Citations

Jul 12, 2018·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Carlos Aguilar
Mar 8, 2018·Hematological Oncology·Giuseppe BorianiPier Luigi Zinzani
Jun 7, 2019·Open Heart·Florian BaptisteFranck Thuny
Sep 18, 2020·Cancer Chemotherapy and Pharmacology·Karen M Fancher, Jeremy J Pappacena
Aug 16, 2019·Wiener klinische Wochenschrift·Markus C StühlingerMichael Steurer
Apr 6, 2019·Current Oncology Reports·Isaac B RheaMichael G Fradley
May 18, 2020·Current Hematologic Malignancy Reports·Masa Lasica, Constantine S Tam
Jun 15, 2021·Expert Opinion on Pharmacotherapy·Chiara CavalloniLuca Arcaini
Jul 27, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·John C ByrdWojciech Jurczak
Aug 4, 2021·Current Oncology Reports·Maude SestierDarryl Leong
Apr 30, 2021·Romanian Journal of Internal Medicine = Revue Roumaine De Médecine Interne·Denisa-Corina CiuculeteGheorghe-Andrei Dan
Sep 1, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Husam Abdel-QadirPaaladinesh Thavendiranathan

❮ Previous
Next ❯

Related Concepts

Related Feeds

CNS Lymphoma

In CNS lymphoma, cancerous cells from lymph tissues or other parts of the body form tumors in the brain and/or spinal cord. Here is the latest research on this rare non-Hodgkin lymphoma.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

B-Cell Leukemia (Keystone)

B-cell leukemia includes various types of lymphoid leukemia that affect B cells. Here is the latest research on B-cell leukemia.