Practice Paradigms Before and After Introduction of the Diagnosis-Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP): an Institutional Experience.

Endocrine Pathology
Levon KatsakhyanZubair W Baloch

Abstract

The recently adopted terminology of "Noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) reflects the indolent behavior of these tumors. In contrast to conventional papillary thyroid carcinomas, NIFTP can be managed conservatively. The purpose of this study was to investigate changes in surgical and pathologic practice patterns at our institution since the introduction of the NIFTP diagnosis in 2016. A retrospective analysis of all thyroid specimens received in our laboratory between January 2015 and April 2017 was performed. The final cohort consisted of 1508 thyroidectomy specimens from 1508 patients (1153 (76.5%) women and 355 (23.5%) men), of which 1011 (67%) were total thyroidectomies and 497 (33%) were partial thyroidectomies. There were 558 (69.2%) total thyroidectomies and 248 (30.8%) partial thyroidectomies performed prior to introduction of the NIFTP diagnosis and 453 (64.5%) and 249 (35.5%) total and partial thyroidectomies, respectively, after the change in nomenclature. Within a year following the initial use of this diagnosis, 67 NIFTP cases were identified (9.5% of all thyroidectomies), whereas compared with the year preceding it, malignant diagnoses decreased from 54.5 (439) to ...Continue Reading

References

Jun 5, 2003·Journal of Clinical Pathology·C E Anderson, K M McLaren
Jul 28, 2016·Thyroid : Official Journal of the American Thyroid Association·Kyle C StricklandJeffrey F Krane
Aug 27, 2016·Cancer Cytopathology·Jeffrey F KraneJustine A Barletta
Sep 19, 2017·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Zubair W BalochUNKNOWN AACE Endocrine Surgery Scientific Committee and Thyroid Scientific Committee
Oct 21, 2017·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Raja R SeethalaLester Dr Thompson
Dec 14, 2018·Journal of the National Comprehensive Cancer Network : JNCCN·Robert I HaddadLisa A Gurski
Jan 2, 2019·Annals of Diagnostic Pathology·Ameer HamzaSajad Salehi
Sep 11, 2019·Thyroid : Official Journal of the American Thyroid Association·Timothy M UllmannToni Beninato

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