Practice Patterns in the Treatment and Monitoring of Acute T Cell-Mediated Kidney Graft Rejection in Canada

Canadian Journal of Kidney Health and Disease
Julie LeblancHéloïse Cardinal

Abstract

One of the goals of the Canadian National Transplant Research Program (CNTRP) is to develop novel therapies for acute rejection that could positively affect graft outcomes with greater efficacy or less toxicity. To develop innovative management strategies for kidney graft rejection, new modalities need to be compared with current clinical practices. However, there are no standardized practices concerning the management of acute T cell-mediated rejection (TCMR). To describe clinicians' practice patterns in the diagnosis, treatment, and monitoring of acute TCMR in Canada. Survey. Canadian transplant nephrologists and transplant surgeons involved in the management of acute TCMR. We developed an anonymous, web-based survey consisting of questions related to the diagnosis, treatment, and monitoring of TCMR. The survey was disseminated on 3 occasions between June and October 2016 through the Canadian Society of Transplantation (CST) kidney group electronic mailing list. Forty-seven respondents, mostly transplant nephrologists (97%), originating from at least 18 of the 25 Canadian centers offering adult or pediatric kidney transplantation, participated in the study. Surveillance biopsies were used by 28% of respondents to screen for k...Continue Reading

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Citations

Dec 1, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Brian J NankivellJeremy R Chapman
Feb 13, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Yassine BouatouCarmen Lefaucheur
Jan 9, 2019·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Ashwin AjithAnatolij Horuzsko
Feb 26, 2020·Human Immunology·Ashwin AjithAnatolij Horuzsko
Jun 30, 2021·Journal of Managed Care & Specialty Pharmacy·Jason T HurwitzDaniel C Malone
Oct 31, 2021·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Christie RampersadChris Wiebe
Dec 4, 2021·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Julie HoAhmed M Abou-Setta

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Methods Mentioned

BETA
biopsies
biopsy

Software Mentioned

FluidSurvey

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