Practice regarding antipsychotic therapy: a cross-sectional survey in two Norwegian hospitals

Nordic Journal of Psychiatry
E JohnsenH A Jørgensen

Abstract

Since the introduction of chlorpromazine, an increasing number of drugs have been added to the list of antipsychotics (neuroleptics). These drugs can be further classified as either first-generation antipsychotics (FAPs) or second-generation antipsychotics (SAPs), depending on their ability to antagonize serotonine in addition to dopamine. The efficacy of various drugs is generally equal, whereas both pharmacological profiles and side-effects differ. Antipsychotic drug therapy recommendations are available both in Norway and internationally, and the purpose of this cross-sectional survey was to register the use of these drugs in representative mental hospitals (A and B), and compare our findings to the recommendations. Medical prescriptions were registered, and data further analysed. In hospital A, a total of 149 patients' prescriptions were registered. Antipsychotics were received voluntarily by 117 patients. Eighty-two of these used one antipsychotic drug, and in this group, 65% received SAPs. Antipsychotic combination therapy was received by 35 patients, and was associated with higher prescription rates of both anticholinergics and benzodiazepines. SAPs were not associated with increased use of benzodiazepines, compared to F...Continue Reading

References

Jun 5, 2001·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·R S McIntyreS H Kennedy
Jun 6, 2002·Schizophrenia Bulletin·Alexander L Miller, Catherine S Craig
Jun 6, 2002·Schizophrenia Bulletin·Stephen R MarderNina R Schooler

❮ Previous
Next ❯

Citations

Jul 1, 2011·Epidemiology and Psychiatric Sciences·L GhioUNKNOWN Research Group
Dec 1, 2005·Annals of General Psychiatry·Ann M MortimerAlison Burrows
Feb 5, 2008·Progress in Neuro-psychopharmacology & Biological Psychiatry·Levent AtikIbrahim Balcioglu
Jan 24, 2017·Nordic Journal of Psychiatry·Niels OkkelsPovl Munk-Jørgensen
Nov 18, 2008·Journal of Clinical Psychopharmacology·Erik JohnsenHugo A Jørgensen
Nov 15, 2019·Nordic Journal of Psychiatry·Hanne HøilundPetter Andreas Ringen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Related Papers

International Clinical Psychopharmacology
K DemyttenaereP Sienaert
Wiener medizinische Wochenschrift
M Siepmann, W Kirch
The British Journal of Psychiatry : the Journal of Mental Science
Del D MillerClinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Investigators
© 2021 Meta ULC. All rights reserved