Jan 1, 1977

Practice related attempts at a precision diagnosis in gynecological cytology

Archiv für Geschwulstforschung
E H WolframE Herold


In a selected material of 316 cases detailed cytological examinations were made, above all, of categories of the Papanicolaou groups III, IV and V. These are special cases with prediagnostically aggravating factors of various, kinds, without and after irradiation therapy. As a comparison, smear-preparations of the Papanicolaou group IV from screening examinations are stated. We aimed at achieving a precisation of cytodiagnostics, so as to achieve in this way the classification to the Papanicolaou groups with a greater reliability. In order to increase the degree of objectivity, the renewed judgements of the preparations by 2 persons (secondary and tertiary diagnostics) were carried through. After the decolorisation of preparations already diagnosed (primary diagnostics) and subsequent renewed judgement after a PAS-reaction test, a significant precisation of the Papanicolaou group III could be reached by a more exact demonstratability of the cell nucleus structures. A strikingly state-blue stainability of the cell nuclei was found significantly more frequently with histologically confirmed carcinomata, less frequently with so-called preliminary stages. There was no statistically significant difference between the preparations ta...Continue Reading

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Cytological Techniques
Test, Cytology, Digestive
Smear Sample
Genital Neoplasms, Female
Staining and Labeling
Papanicolaou Test
Pap Smear
Cytology Procedure

About this Paper

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Coronavirus Protein Structures

Deciphering and comparing the proteins of different coronaviruses forms a basis for understanding SARS-CoV-2 evolution and virus-receptor interactions. This feed follows studies analyzing the structures of coronavirus proteins, thereby revealing potential drug target sites.

DDX3X Syndrome

DDX3X syndrome is caused by a spontaneous mutation at conception that primarily affects girls due to its location on the X-chromosome. DDX3X syndrome has been linked to intellectual disabilities, seizures, autism, low muscle tone, brain abnormalities, and slower physical developments. Here is the latest research.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research.

Fusion Oncoproteins in Childhood Cancers

This feed explores the function of fusion oncoproteins in specific childhood cancers, including those from racial/ethnic minority and underserved groups, and to provide preclinical assessment of potential therapeutics and how fusion oncoproteins influence gene expression to perturb normal cellular programs to block lineage differentiation and development

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Mitotic-exit networks with cytokinesis

Cytokinesis is the highly regulated process that physically separates daughter and mother cells in late mitosis. The mitotic-exit network (MEN), the signalling pathway that drives mitotic exit, directly regulates cytokinesis. Discover the latest research on mitotic-exit networks with cytokinesis here.

DNA Replication Origin

DNA replication is initiated as specific gene sequences, called origins, that function to start DNA replication. Pre-replication complexes are assembled at these origins during the G1 phase of the cell cycle. These sequences allow for targeted activation or deactivation of replication. Discover the latest research on DNA replication origins here.

© 2020 Meta ULC. All rights reserved