Practice trends in use of morphine for control of intraoperative pain: An audit.

Journal of Anaesthesiology, Clinical Pharmacology
Ajai Kumar JainAsha Tyagi

Abstract

When using morphine as the sole analgesic during conduct of anesthesia, the fear of its adverse postoperative effects primarily sedation and respiratory depression may impede adequate dosing and analgesia. This audit aims to explore the dosing schedules of morphine used during general anesthesia in our institution and to analyze whether the fear of major side effects leads to suboptimal dosing of morphine with inadequate pain relief. All subjects scheduled for surgery under general anesthesia wherein morphine was used exclusively for intraoperative analgesia were included in the audit. The audit proforma was completed by the attending anesthesiologist wherein the study period extended from beginning of anesthesia to immediate postoperative period. The study population comprised of 158 patients having mean age 33 ± 14 years and mean weight 52 ± 14 kg. The dose of morphine administered at induction varied widely from 0.05 to 0.3 mg/kg i.v. The VAS (Visual Analogue Scale) score in immediate postoperative period varied from 0 to 10 (mean 1.7 ± 2.0) and sedation score from 1 to 5 (mean 3.94 ± 1.05). Inadequate analgesia with a VAS score ≥4 was seen in 15% patients. Morphine dosage of >0.1 mg/kg was associated with highly significant...Continue Reading

Citations

Jul 1, 2017·Anesthesia, Essays and Researches·Keelara Shivalingaiah SavithaApoorwa N Kothari

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