journal cover

Prdm9 controls activation of mammalian recombination hotspots

Science

Jan 2, 2010

Emil D ParvanovKenneth Paigen

Abstract

Mammalian meiotic recombination, which preferentially occurs at specialized sites called hotspots, ensures the orderly segregation of meiotic chromosomes and creates genetic variation among offspring. A locus on mouse chromosome 17, which controls activation of recombination at multiple...read more

Mentioned in this Paper

Zinc Fingers
Histone antigen
Biological Regulation
PRDM9 gene
Recombination, Genetic
House mice
Meiotic Recombination
Genome Mapping
Staphylococcal Protein A
Testis
7
271
1
Paper Details
References
  • References8
  • Citations253
1
  • References8
  • Citations253
12345...

Similar Papers Found In These Feeds

General Biology Journal eTOCs

Discover the latest general biology research in this collection of the top biology journals.

Science eTOC

Science Magazine is a peer-reviewed academic journal of the American Association for the Advancement of Science. Find the latest research from Science here.

Zinc Finger Nucleases

Zinc-finger nucleases are engineered restriction enzymes that enable gene editing by targeting specific DNA sequences in the genome. Here is the latest research.

Nature | Cell | Science

Discover the latest research from the prestigious journals: Nature, Cell, and Science.

Related Papers

© 2020 Meta ULC. All rights reserved

Prdm9 controls activation of mammalian recombination hotspots

Science

Jan 2, 2010

Emil D ParvanovKenneth Paigen

PMID: 20044538

DOI: 10.1126/science.1181495

Abstract

Mammalian meiotic recombination, which preferentially occurs at specialized sites called hotspots, ensures the orderly segregation of meiotic chromosomes and creates genetic variation among offspring. A locus on mouse chromosome 17, which controls activation of recombination at multiple...read more

Mentioned in this Paper

Zinc Fingers
Histone antigen
Biological Regulation
PRDM9 gene
Recombination, Genetic
House mice
Meiotic Recombination
Genome Mapping
Staphylococcal Protein A
Testis
7
271
1

Similar Papers Found In These Feeds

General Biology Journal eTOCs

Discover the latest general biology research in this collection of the top biology journals.

Science eTOC

Science Magazine is a peer-reviewed academic journal of the American Association for the Advancement of Science. Find the latest research from Science here.

Paper Details
References
  • References8
  • Citations253
1
  • References8
  • Citations253
12345...
/papers/prdm9-controls-activation-of-mammalian/20044538