Pre- and postoperative anemia, acute kidney injury, and mortality after coronary artery bypass grafting surgery: a retrospective observational study

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
Adriana D OpreaMiklos D Kertai

Abstract

Preoperative and postoperative anemia have been identified individually as potential risk factors for postoperative complications after coronary artery bypass grafting (CABG) surgery. Their interrelationship with acute kidney injury (AKI) and long-term mortality, however, has not been clearly defined and was the purpose of this study. We retrospectively evaluated 6,130 adult patients undergoing CABG surgery performed at a single large academic medical center. Preoperative and postoperative hemoglobin concentrations were used as continuous predictors of postoperative AKI and mortality. Additionally, sex-specific preoperative (< 13 g·dL-1 in men and < 12 g·dL-1 in women) and postoperative anemia (the median of the lowest in-hospital values) were used as categorical predictors. AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guidelines, when serum creatinine rose ≥ 50% during the period between day of surgery and postoperative day ten, or when a 0.3 mg·dL-1 (26.5 μmol·L-1) increase was detected in a rolling 48-hr window from the day of surgery to the tenth postoperative day. The association of preoperative and postoperative hemoglobin levels and anemia patterns with postoperativ...Continue Reading

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Citations

Aug 8, 2019·Annals of Intensive Care·Joana Gameiro, José António Lopes
Jul 5, 2021·The Annals of Thoracic Surgery·Pierre TibiSusan Moffatt-Bruce
Jul 5, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Pierre TibiSusan Moffatt-Bruce
Aug 14, 2021·Journal of Orthopaedics·Abhishek GantaKenneth A Egol
Jul 1, 2020·Cardiorenal Medicine·Faeq Husain-SyedClaudio Ronco

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