PMID: 7018644Mar 1, 1981Paper

Pre-anaesthetic medication in paediatric day-care surgery

Canadian Anaesthetists' Society Journal
R DesjardinsJ Charest

Abstract

Pre-anaesthetic medication has the primary aim of making the whole process of anaesthesia smooth and agreeable. This prospective blind study was planned to compare the efficacy of three active drugs and a placebo as premedication in a paediatric population undergoing operation on a day care basis. One hundred and fifty-nine patients between one and 12 years of age were assigned randomly to one of four groups who received either hydroxyzine 0.5 mg . kg-1 (n - 43) promethazine 0.5 mg . kg-1 (n 40) diazepam 0.1 mg . kg (n - 378) or placebo (n - 36) by mouth, 60 minutes before operation. Observations in the operating room included the emotional state of the patient on arrival, quality of induction and complications. In the recovery room time for emergence from anaesthesia, complications and requirements for analgesia were recorded. The parents were asked for return a questionnaire detailing psychological and physical complications during three postoperative days. There was no difference between the groups in any of the factors examined. From this study we conclude that children undergoing surgical operations and anaesthesia on a day care basis should not receive pharmacological premedication, not because of overwhelming risk from i...Continue Reading

References

Jan 1, 1976·Canadian Anaesthetists' Society Journal·G Gale, S Galloon
Nov 19, 1977·Lancet
Sep 1, 1977·Anesthesiology·W H ForrestB W Brown
Dec 8, 1979·British Medical Journal·J Oosterlee, H A Dudley
Jun 1, 1979·British Journal of Anaesthesia·H J McQuayA P Adams
Nov 1, 1979·British Journal of Anaesthesia·P D Booker, D H Chapman
Apr 1, 1978·Anesthesiology·J T Conner
Apr 1, 1978·Anaesthesia·A Gilston
Jan 1, 1979·Canadian Anaesthetists' Society Journal·H T MaguireJ B Gattinella
Jun 1, 1977·British Journal of Anaesthesia·W WassenaarG D Gale
May 1, 1977·Canadian Anaesthetists' Society Journal·G M Urbach, G Edelist
Oct 15, 1977·British Medical Journal·J M LeighP Janaganathan
Jan 1, 1976·International Anesthesiology Clinics·K F SchmidtK Korten
Aug 1, 1975·Anesthesiology·B M Korsch
Aug 1, 1975·Anesthesiology·D J Steward
Sep 1, 1975·Canadian Anaesthetists' Society Journal·G F Brindle, M G Soliman
Jan 11, 1975·International Anesthesiology Clinics·B R Brown, D G Geha
Jun 26, 1976·British Medical Journal·J E SimpsonS Folkard
Jan 1, 1971·International Anesthesiology Clinics·W Norris
Sep 1, 1973·Canadian Anaesthetists' Society Journal·R A Barker, H I Nisbet
Dec 9, 1972·British Medical Journal·T W Ogg
Nov 1, 1973·Anesthesia and Analgesia·D J Steward
Aug 1, 1970·The Surgical Clinics of North America·K Sewall
Jan 1, 1957·Anesthesiology·R P CUTLER, L FRANCIS
Jul 1, 1962·British Journal of Anaesthesia·J W DUNDEER M NICHOLL
Oct 1, 1963·British Journal of Anaesthesia·H I NISBET, W NORRIS

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Citations

Sep 1, 1983·Canadian Anaesthetists' Society Journal·G G Johnson
Jan 1, 1982·Canadian Anaesthetists' Society Journal·B Kay
Nov 1, 1986·Canadian Anaesthetists' Society Journal·N C Wilton, J M Burn
May 1, 1987·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·T H Madej, R T Paasuke

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