PMID: 6447787Jun 1, 1980Paper

Pre-atherosclerotic lesions in Down syndrome

Journal of Mental Deficiency Research
T J Moss, G E Austin


Autopsy examination of seven non-institutionalised Down syndrome patients (age ten to twenty-five years) revealed normal prevalence of pre-atherosclerotic lesions. Atherosclerotic plaques were observed in one of these subjects (age fourteen years), refuting reported implications that this population is atheroma-free. However, atheromatous aortic lesions were not seen in an eighth subject (age fifty years), raising the possibility that an atheroma-free subgroup of patients with Down syndrome may exist.


Mar 1, 1975·Acta paediatrica Scandinavica·J OsterA Nielsen
Jul 23, 1977·British Medical Journal·J C MurdochM G Dunnigan
Jan 1, 1979·The Journal of Pediatrics·T J MossA J Moss
Aug 12, 1976·The New England Journal of Medicine·R Ross, J A Glomset

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.