PMID: 6447787Jun 1, 1980Paper

Pre-atherosclerotic lesions in Down syndrome

Journal of Mental Deficiency Research
T J Moss, G E Austin

Abstract

Autopsy examination of seven non-institutionalised Down syndrome patients (age ten to twenty-five years) revealed normal prevalence of pre-atherosclerotic lesions. Atherosclerotic plaques were observed in one of these subjects (age fourteen years), refuting reported implications that this population is atheroma-free. However, atheromatous aortic lesions were not seen in an eighth subject (age fifty years), raising the possibility that an atheroma-free subgroup of patients with Down syndrome may exist.

References

Mar 1, 1975·Acta paediatrica Scandinavica·J OsterA Nielsen
Jul 23, 1977·British Medical Journal·J C MurdochM G Dunnigan
Jan 1, 1979·The Journal of Pediatrics·T J MossA J Moss
Aug 12, 1976·The New England Journal of Medicine·R Ross, J A Glomset

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