[Pre-emptive analgesia-prophylaxis of postoperative pain.].

Der Schmerz
I Kiss

Abstract

Pain prophylaxis is an everyday experience in clinical anaesthesia. There is now considerable experimental evidence that short-term nociceptive stimuli evoke a long-lasting excitatory state of the central nervous system. This excitatory state can be largely prevented by relatively small doses of anaesthetics (local anaesthetics, opioids) given prelesionally. Suchpre-emptive analgesia is the theoretical basis of the clinical experience cited above. This experimental knowledge has clinical applications in the field of postoperative analgesia-which, as is well known, is the Cinderella of anaesthesia. Al-thoughs sound knowledge of the methods is available, postoperative pain relief is very often inadequate. because of organizational difficulties. Pre-emptive analgesia reduces the frequency and intensity of postoperative pain. Infiltration of the surgical incision with local anaesthetics, regional blockades, and spinal and epidural analgesia, all performed preoperatively, and also the administration of analgesies with the premedication, produce postoperative analgesia lasting longer than the known duration of any of these alone. The efficiency of these methods has been scientifically proved during recent years. Pre-emptive analgesia...Continue Reading

References

Jun 1, 1992·Pain·W A MacraeI K Crombie
Apr 1, 1992·British Journal of Anaesthesia·G W DierkingH Kehlet
Dec 1, 1991·Anesthesia and Analgesia·S M SteeleJ G Reves
Oct 1, 1990·British Journal of Anaesthesia·G L HutchisonI G Gray
Jan 1, 1990·Anesthesia and Analgesia·M TverskoyI Kissin
May 1, 1989·Acta Anaesthesiologica Scandinavica·R LevinL Vavruch
Aug 1, 1989·British Journal of Anaesthesia·C J Woolf
Aug 1, 1989·British Journal of Anaesthesia·H Kehlet
Jun 1, 1987·Anesthesiology·M P YeagerT Brinck-Johnsen
Jun 1, 1988·Pain·P D Wall
May 2, 1953·British Medical Journal·D L LEWIS, W A L THOMPSON

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