Pre-Emptive Avoidance Strategy (P.E.A.S.) - addressing allergic contact dermatitis in pediatric populations

Expert Review of Clinical Immunology
Hannah HillSharon E Jacob

Abstract

Pediatric allergic contact dermatitis (ACD) has been increasingly recognized in the United States. Reported rates of positive patch tests in children referred for suspected ACD range between 27 and 95.6%. Many young children are becoming sensitized to contact allergens found in personal hygiene products. We reviewed five recent pediatric patch test studies to determine the top allergens associated with this source of ACD in children. The top ten allergens were neomycin, balsam of Peru, fragrance mix, lanolin, cocamidopropylbetaine, formaldehyde, corticosteroids, methylchlorisothiazolinone (MCI)/methylisothiazolinone (MI), propylene glycol, and benzalkonium chloride. We estimate that one third of children suffering from ACD could potentially benefit from a 'pre-emptive avoidance strategy' (P.E.A.S.) of the stated top 10 allergens.

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Citations

Nov 20, 2016·Expert Review of Clinical Immunology·Nikoleta Brankov, Sharon E Jacob
Jun 10, 2016·Journal of Telemedicine and Telecare·Sharon E JacobAlina Goldenberg
Sep 9, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Jahdonna Isaac, Pamela L Scheinman
Aug 3, 2018·Current Allergy and Asthma Reports·Calvin T SungSharon E Jacob
Apr 2, 2019·The British Journal of Dermatology·A Goldenberg, S E Jacob
Oct 25, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Maria A McGowanSharon E Jacob
Apr 18, 2020·Pediatric Dermatology·Idy Tam, JiaDe Yu
Sep 21, 2016·Dermatitis : Contact, Atopic, Occupational, Drug·Alina GoldenbergSharon E Jacob
Jul 4, 2020·Current Opinion in Pediatrics·Idy Tam, JiaDe Yu
May 26, 2017·Pediatric Dermatology·Sharon E JacobAlina Goldenberg
Jun 18, 2020·Current Allergy and Asthma Reports·Idy Tam, JiaDe Yu
Aug 19, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·Jodie RaffiNina Botto
Jul 14, 2016·BMC Dermatology·Hossein MortazaviEbrahim Arian
Sep 19, 2018·Clinical Reviews in Allergy & Immunology·Jenna BorokSharon E Jacob
Nov 21, 2020·Journal of the American Academy of Dermatology·Holly NealeJiaDe Yu
Jul 7, 2021·Immunology and Allergy Clinics of North America·Christen Brown, JiaDe Yu
Jul 7, 2021·Immunology and Allergy Clinics of North America·Mohsen BaghchechiSharon E Jacob
Sep 29, 2021·Journal of the American Academy of Dermatology·Jonathan I SilverbergMarie-Claude Houle
Apr 29, 2020·Pediatrics·Nanette B SilverbergUNKNOWN SECTION ON DERMATOLOGY, SECTION ON ALLERGY AND IMMUNOLOGY

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