Pre-emptive meloxicam for postoperative analgesia in piglets undergoing surgical castration

Veterinary Anaesthesia and Analgesia
Alassane KeitaChristian Guidarini

Abstract

To investigate the effect of preoperative meloxicam administration on postoperative stress and pain induced by surgical castration in piglets. Prospective, blinded, randomized clinical trial. One hundred and eighty male piglets of <1 week of age. Castration was performed on 150 piglets which had received either an intramuscular injection of 0.4 mg kg(-1) meloxicam or a placebo 10-30 minutes before the procedure. Blood cortisol and ACTH concentrations were determined at 30 minutes post-castration and haptoglobin was measured at 24 hours post-castration. Presence or absence of foreleg movements, hind leg movements, urine or faeces emission, tremors or other body movements were recorded during the castration procedure. Scores for presence or absence of prostration, tremors, tail movements and isolation were recorded at 30 minutes, and at 1, 2, 4 and 24 hours post-castration and combined in a global behaviour score (GBS). Blood samples were taken from a further 30 piglets which did not undergo castration. Mean blood cortisol and ACTH concentrations at 30 minutes post-castration were both significantly lower in the meloxicam group than in the placebo group (p < or = 0.01). The mean haptoglobin concentration at 24 hours was not signi...Continue Reading

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