Pre-Exposure Prophylaxis (PrEP) for Safer Conception Among Serodifferent Couples: Findings from Healthcare Providers Serving Patients with HIV in Seven US Cities

AIDS Patient Care and STDs
Sarah Finocchario-KesslerJean Anderson

Abstract

Pre-exposure prophylaxis (PrEP) can reduce the risk of HIV transmission among serodifferent couples trying to conceive, yet provider knowledge, attitudes, and experience utilizing PrEP for this purpose are largely unexamined. Trained interviewers conducted phone interviews with healthcare providers treating patients with HIV in seven cities (Atlanta, Baltimore, Houston, Kansas City, Newark, Philadelphia, and San Francisco, N = 85 total). Quantitative and qualitative data were analyzed to describe experience, concerns, and perceived barriers to prescribing PrEP for safer conception. Providers (67.1% female, 43 mean years of age, 70.4% white, 10 mean years treating HIV+ patients, 56% in academic vs. community facilities, 62.2% MD) discussed both benefits and concerns of PrEP for safer conception among serodifferent couples. Only 18.8% of providers reported experience prescribing PrEP, 74.2% were willing to prescribe it under ideal circumstances, and 7.0% were not comfortable prescribing PrEP. Benefits included added protection and a greater sense of control for the HIV-negative partner. Concerns were categorized as clinical, system-level, cost, or behavioral. Significant differences in provider characteristics existed across site...Continue Reading

References

May 21, 2010·AIDS Patient Care and STDs·Sarah Finocchario-KesslerJean R Anderson
Nov 26, 2010·The New England Journal of Medicine·Robert M GrantUNKNOWN iPrEx Study Team
Mar 31, 2011·AIDS Patient Care and STDs·Kathleen E SquiresJudith A Aberg
Apr 5, 2011·American Journal of Obstetrics and Gynecology·Margaret A LampeSteven R Nesheim
Apr 12, 2011·AIDS Care·Susan CliffeMarie-Louise Newell
Jul 13, 2012·The New England Journal of Medicine·Jared M BaetenUNKNOWN Partners PrEP Study Team
Jul 13, 2012·The New England Journal of Medicine·Michael C ThigpenUNKNOWN TDF2 Study Group
Sep 5, 2012·Pediatrics·Steven NesheimJonathan Mermin
May 3, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Deborah DonnellConnie Celum
Jul 20, 2014·JAMA : the Journal of the American Medical Association·Nelly R MugoUNKNOWN Partners PrEP Study Team
Aug 15, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Lynn T MatthewsUNKNOWN Partners PrEP Study Team
Sep 16, 2014·Journal of AIDS & Clinical Research·Lisa RahangdaleCatherine Grodensky
Sep 27, 2014·AIDS·Edwin O WereUNKNOWN Partners PrEP Study Team
Oct 9, 2014·AIDS Patient Care and STDs·Charlene A FlashKenneth H Mayer

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Citations

Jul 16, 2017·The Journal of the Association of Nurses in AIDS Care : JANAC·Megan OrlandoDominika Seidman
Mar 20, 2016·Current HIV/AIDS Reports·Renee HeffronNelly Mugo
May 20, 2020·The Journal of the Association of Nurses in AIDS Care : JANAC·Jack J MayeuxMatthew M Bice
Dec 22, 2020·The Journal of the Association of Nurses in AIDS Care : JANAC·Joanne Phillips SimoneDeborah S Storm
Jan 4, 2021·Maternal and Child Health Journal·Roxanne Mirabal-BeltranSarah Finocchario-Kessler
May 25, 2021·Inquiry : a Journal of Medical Care Organization, Provision and Financing·Robert L CooperMarybeth Shinn

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