Pre-frailty factors in community-dwelling 40-75 year olds: opportunities for successful ageing

BMC Geriatrics
S J GordonK A Grimmer

Abstract

There is little known about pre-frailty attributes or when changes which contribute to frailty might be detectable and amenable to change. This study explores pre-frailty and frailty in independent community-dwelling adults aged 40-75 years. Participants were recruited through local council networks, a national bank and one university in Adelaide, Australia. Fried frailty phenotype scores were calculated from measures of unintentional weight loss, exhaustion, low physical activity levels, poor hand grip strength and slow walking speed. Participants were identified as not frail (no phenotypes), pre-frail (one or two phenotypes) or frail (three or more phenotypes). Factor analysis was applied to binary forms of 25 published frailty measures Differences were tested in mean factor scores between the three Fried frailty phenotypes and ROC curves estimated predictive capacity of factors. Of 656 participants (67% female; mean age 59.9 years, SD 10.6) 59.2% were classified as not frail, 39.0% pre-frail and 1.8% frail. There were no gender or age differences. Seven frailty factors were identified, incorporating all 25 frailty measures. Factors 1 and 7 significantly predicted progression from not-frail to pre-frail (Factor 1 AUC 0.64 (95...Continue Reading

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Citations

Aug 4, 2020·Health & Social Care in the Community·Angela Yee Man LeungRenli Deng
Aug 30, 2020·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Pascale Le Maguet, Gildas Gueret
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Dec 23, 2020·International Journal of Environmental Research and Public Health·An-Chen ShihJau-Yuan Chen
Jan 8, 2021·Clinical Interventions in Aging·Christiane VölterJan Peter Thomas
Mar 9, 2021·Frontiers in Aging Neuroscience·Naina Yuki Vieira JardimCristovam Wanderley Picanço Diniz

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