PMID: 8942879Nov 1, 1996Paper

Pre-injection fluorescence in indocyanine green angiography

Ophthalmology
F C PiccolinoS Torrielli

Abstract

To verify whether infrared pre-injection fluorescence can be observed in patients undergoing indocyanine green (ICG) angiography. Infrared fundus photographs were taken before dye injection for 450 consecutive patients undergoing ICG angiography for different chorioretinal disorders. The authors used a high-resolution videoangiography system with the standard ICG filters inserted (overlap, < 0.5%) and the highest flash intensity. Pre-injection fluorescence was detected in 184 patients (40.8%). It was a strong fluorescence in 75 patients (40.7%) and a faint fluorescence in 109 (59.2%). When fluorescence was strong, it simulated vascular filling on the ICG angiogram. Pre-injection fluorescence resulted from the following lesions: (1) old grayish subretinal hemorrhages (35 patients); (2) lipofuscin-like deposits (65 patients); (3) pigmented choroidal neovascular membranes (72 patients); and (4) serous retinal detachments lasting from several months or years (12 patients). Highly reflecting white lesions were not fluorescent. Pre-injection fluorescence of chorioretinal lesions is frequently detectable in patients with diseases requiring ICG examination. A pre-injection photograph may help to avoid misinterpretation of the angiogram...Continue Reading

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Citations

Oct 12, 2011·Archives of Ophthalmology·Catherine A CukrasPaul A Sieving
Apr 17, 2008·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·T TheelenC B Hoyng
Jan 16, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Weiju WuDezheng Wu
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Apr 13, 2007·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Artur V CideciyanSamuel G Jacobson
Jan 25, 2012·Acta Ophthalmologica·Raimondo ForteEric H Souied
Dec 3, 2016·Archivos de la Sociedad Española de Oftalmología·J Ruiz-MedranoJ M Ruiz-Moreno
Nov 4, 2017·Acta Ophthalmologica·Francesco PichiArif O Khan
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Nov 21, 2012·Seminars in Ophthalmology·Dimitra SkondraDemetrios G Vavvas
Jan 12, 2020·Communications Biology·Guillaume NormandSudeep Chandra
Dec 12, 2018·Journal of Biological Engineering·Maryse Lapierre-LandryMelissa C Skala
Dec 10, 2020·PloS One·Masaaki SaitoTetsuju Sekiryu
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Mar 31, 2021·Klinische Monatsblätter für Augenheilkunde·Johannes BirtelPeter Charbel Issa

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