Pre-Operative Left Ventricular Torsion, QRS Width/CRT, and Post-Mitral Surgery Outcomes in Patients With Nonischemic, Chronic, Severe Secondary Mitral Regurgitation

JACC. Basic to Translational Science
Yuichi NotomiKoji Furukawa

Abstract

The selection of appropriate candidates for mitral surgery among symptomatic patients with nonischemic, chronic, secondary severe mitral regurgitation (NICSMR) remains a clinical challenge. We studied 50 consecutive symptomatic NICSMR patients for a median follow-up of 2.5 years after mitral surgery and concluded that the pre-operative 2-dimensional speckle tracking echocardiography-derived left ventricular torsional profile and QRS width/cardiac resynchronization therapy are potentially important prognostic indicators for post-surgery survival and reverse remodeling.

References

Feb 1, 1969·Biophysical Journal·I Mirsky
Apr 20, 2001·The Annals of Thoracic Surgery·A M CalafioreG Di Giammarco
Jun 28, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jan F GummertFriedrich W Mohr
Jun 21, 2005·Journal of the American College of Cardiology·Yuichi NotomiJames D Thomas
Nov 23, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Yuichi NotomiJames D Thomas
Jun 3, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Borut KirnFrits W Prinzen
Feb 2, 2010·Journal of the American College of Cardiology·Thomas G Di SalvoJohn G Byrne
Jan 29, 2011·The Journal of Thoracic and Cardiovascular Surgery·Michael A AckerSpencer H Kubo
Nov 15, 2011·Journal of the American College of Cardiology·Angelo AuricchioUNKNOWN PERMIT-CARE Investigators
Aug 28, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alec VahanianUNKNOWN European Association for Cardio-Thoracic Surgery (EACTS)
Nov 20, 2012·Journal of the American College of Cardiology·Douglas L MannDaniel Burkhoff
Feb 25, 2014·Circulation. Heart Failure·Elisa F LongAbeel A Mangi
Dec 30, 2014·Journal of the American College of Cardiology·Paul A GrayburnRobert J Siegel
Jan 7, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Roberto M LangJens-Uwe Voigt
Mar 21, 2015·Journal of the American College of Cardiology·Seth UretskySteven D Wolff
Mar 31, 2015·Journal of the American College of Cardiology·Anita W AsgarGregg W Stone

❮ Previous
Next ❯

Citations

Nov 15, 2018·Journal of Cardiovascular Development and Disease·Marco Cirillo
Sep 22, 2017·Nature Reviews. Cardiology·Gene H KimDaniel Burkhoff
Feb 28, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoshihiro SeoKazutaka Aonuma
Mar 13, 2018·European Heart Journal Cardiovascular Imaging·Juan Manuel Monteagudo RuizJosé Luis Zamorano

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT01626079

Software Mentioned

Statistical Package Excel Statistics
R Foundation
R

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.