Pre-operative lymphoscintigraphy before sentinel lymph node biopsy for breast cancer

The Breast : Official Journal of the European Society of Mastology
M A MathewA Nejim

Abstract

Pre-operative lymphoscintigram for axillary sentinel lymph node biopsy (SLNB) may not be required for successful SLNB. The 117 consecutive patients who underwent SLNB had pre-operative lymphoscintigraphy. The operating surgeon was blinded to the results of the lymphoscintigram before SLNB. After SLNB was complete, the surgeon was unblinded to the results of the lymphoscintigram; re-exploration carried out if more nodes were predicted on the lymphoscintigram. 116 patients (99%) had successful SLNB before unblinding. In 85 patients (73%), operative findings corresponded with scintigraphic findings. In 26 patients (22%), the lymphoscintigram predicted more sentinel nodes than had been found; further nodes were identified and excised in only 4 patients (3%). None were positive for cancer. SLNB was successful in 99% of cases without pre-operative lymphoscintigraphy. Only 3% of patients had further nodes identified as a result of the lymphoscintigram. Pre-operative lymphoscintigraphy does not improve the ability to perform axillary SLNB during breast cancer surgery.

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Citations

Dec 22, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Sergi Vidal-SicartRenato A Valdés-Olmos
Jul 10, 2010·Current Opinion in Oncology·Maaike H M OonkAte G J van der Zee
Feb 4, 2014·The Breast : Official Journal of the European Society of Mastology·Marc ThillNik Hauser
Jan 25, 2014·The Breast : Official Journal of the European Society of Mastology·J H VoldersW K De Roos

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