PMID: 16518287Mar 7, 2006Paper

Pre-operative predictive factors of early recurrence after resection of adenocarcinoma of the esophagus and cardia

Gastroentérologie Clinique Et Biologique
Frédéric MalBrice Gayet

Abstract

To determine pre-operative predictive factors of early recurrence in patients with esophageal and cardial adenocarcinoma. We retrospectively analyzed consecutive patients who underwent resection for esophageal and cardial adenocarcinoma in our institution between October 1992 and October 2001. Patient files were studied and classified according to the occurrence of early recurrence (within one year) (group A) and patients without recurrence (group B). Pre-operative clinical, biological and radiological parameters were recorded. Both groups were compared in univariate and multivariate analysis. One hundred patients underwent surgical resection. Tumor was located in lower esophagus in 71 cases and at the cardia in 29 cases. R0 resection was feasible in 95 cases. Hospital mortality was 2%. Survival rate at 3 years was 56%. Recurrence before 1 year occurred in 28 patients (group A) and not in 72 (group B). In univariate analysis, younger age (P=0.01), dysphagia (P=0.04) and percentage of weight loss (P<0.0004) were significantly different between both groups. Weight loss more than 10% was observed in 2 patients of group B, and in 9 patients of group A. In multivariate analysis, weight loss more than 10% was the only pre-operative f...Continue Reading

References

Aug 15, 1996·The New England Journal of Medicine·T N WalshT P Hennessy
Dec 31, 1998·The New England Journal of Medicine·D P KelsenJ A Roth
Jun 7, 2002·Lancet·UNKNOWN Medical Research Council Oesophageal Cancer Working Group
Nov 22, 2002·The New England Journal of Medicine·Jan B F HulscherJ Jan B van Lanschot
Dec 6, 2003·The New England Journal of Medicine·Peter C Enzinger, Robert J Mayer

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Citations

Sep 6, 2012·Journal of Surgical Oncology·Fangxuan LiJichuan Quan
Jun 20, 2015·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·F KongY Jia
Jan 8, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Hans Van VeerPhilippe Nafteux
Aug 8, 2015·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·R B StrandbyM P Achiam
Jun 29, 2017·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·O HynesP Lagergren
Apr 24, 2008·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·L A HealyJ V Reynolds

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