Pre-procedural glucose levels and the risk for contrast-induced acute kidney injury in patients undergoing emergency coronary intervention

Circulation Journal : Official Journal of the Japanese Circulation Society
Hiroyuki NaruseYukio Ozaki

Abstract

The incidence, risk factors, and outcome of contrast-induced acute kidney injury (CI-AKI) in 730 patients with acute coronary syndrome (ACS) undergoing emergency percutaneous coronary intervention (PCI), whose contrast volume was below maximum allowable contrast dose (MACD) was prospectively investigated. MACD was defined as (5ml×body weight [kg]/baseline creatinine [mg/dl]). CI-AKI was defined as a greater than 25% increase in creatinine from the baseline or an absolute increase of ≥0.5mg/dl within 48h after the procedure. CI-AKI occurred in 212 (29%) patients. Patients with CI-AKI had a higher risk for in-hospital mortality (9.4% vs. 1.5%, P<0.001) and a longer stay in the coronary care unit (median, 4.0 vs. 3.0 days, P<0.001) compared with those without CI-AKI. In a multivariate logistic analysis including 20 clinical variables, elevated glucose levels as variables categorized into quartiles were independently (P<0.001) associated with the development of CI-AKI. In addition, this relationship was seen in both the subgroup of patients with known diabetes and that of those without known diabetes. CI-AKI might occur commonly and could be be associated with a more complicated clinical course in ACS patients undergoing emergency ...Continue Reading

References

Jun 1, 1989·The American Journal of Medicine·R G CigarroaL D Hillis
Oct 15, 1989·The American Journal of Cardiology·G BellodiG Rossi
Dec 31, 1997·The American Journal of Medicine·P A McCulloughW W O'Neill
Jul 10, 1999·Journal of the American College of Cardiology·H KawanoH Yasue
Aug 18, 2000·The Journal of Clinical Endocrinology and Metabolism·P MohantyP Dandona
Nov 9, 2002·The American Journal of Cardiology·Rosario V FreemanUNKNOWN Blue Cross-Blue Shield of Michigan Cardiovascular Consortium (BMC2)
Mar 26, 2003·Journal of the American College of Cardiology·Paolo GreseleGeremia B Bolli
Aug 14, 2003·The American Journal of Cardiology·Vandana MenonRobert J Goldberg
Oct 29, 2003·Archives of Internal Medicine·Christopher B GrangerUNKNOWN Global Registry of Acute Coronary Events Investigators
Nov 3, 2004·Journal of the American College of Cardiology·Giancarlo MarenziAntonio L Bartorelli
Sep 5, 2006·The American Journal of Cardiology·James TumlinUNKNOWN CIN Consensus Working Panel
Sep 5, 2006·The American Journal of Cardiology·Fulvio StaculUNKNOWN CIN Consensus Working Panel
Feb 27, 2008·Circulation·Prakash DeedwaniaUNKNOWN American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism
Apr 3, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Seiichi MatsuoUNKNOWN Collaborators developing the Japanese equation for estimated GFR
Jun 19, 2009·Kidney International·Ilse VanhorebeekGreet Van den Berghe
Apr 3, 2010·Journal of the American College of Cardiology·Joshua M StolkerMikhail Kosiborod
May 15, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Noriaki KumeToru Kita
Jul 1, 2010·Circulation. Cardiovascular Interventions·Jeremiah R BrownDavid J Malenka
Dec 15, 2010·American Heart Journal·Giancarlo MarenziAntonio L Bartorelli

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Citations

Apr 4, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·Noriaki MoriyamaHisao Ogawa
Feb 6, 2017·Journal of the American Heart Association·Wen-Jun YinXiao-Cong Zuo
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Aug 30, 2013·Circulation Journal : Official Journal of the Japanese Circulation Society·Gen IgarashiHiroshi Ito
Oct 11, 2013·Circulation Journal : Official Journal of the Japanese Circulation Society·Daisuke AbeKazutaka Aonuma

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