Pre-Procedural Thrombolysis in Myocardial Infarction Flow in Patients with ST-Segment Elevation Myocardial Infarction

International Heart Journal
Takuya HashimotoJ-MINUET investigators

Abstract

It has been shown that the patency of an infarct-related artery (IRA) before primary percutaneous coronary intervention determines post-procedural success, better preservation of left ventricular function, and lower in-hospital mortality. However, the factors associated with pre-procedural Thrombolysis In Myocardial Infarction (TIMI) flow have not been fully investigated.The Japanese registry of acute Myocardial INfarction diagnosed by Universal dEfiniTion (J-MINUET) is a prospective multicenter registry conducted at 28 Japanese medical institutions between July 2012 and March 2014. We enrolled 3,283 consecutive patients with acute myocardial infarction who were admitted to a participating institution within 48 hours of symptom onset. There were 2,262 patients (68.9%) with ST-elevation myocardial infarction (STEMI), among whom 2,182 patients underwent emergent or urgent coronary angiography.Pre-procedural TIMI flow grade 3 was related to post-procedural TIMI flow grade 3 (P < 0.001), lower enzymatic infarct size (P < 0.001), lower ventricular tachycardia and ventricular fibrillation (P = 0.049), and lower in-hospital mortality (P = 0.020). A history of antiplatelet drug use was associated with pre-procedural TIMI flow.Antiplate...Continue Reading

References

Nov 5, 1999·The New England Journal of Medicine·F ZijlstraH Suryapranata
Dec 8, 2000·Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology·G Bernardi
Jun 23, 2001·The New England Journal of Medicine·G MontalescotUNKNOWN ADMIRAL Investigators. Abciximab before Direct Angioplasty and Stenting in Myocardial Infarction Regarding Acute and Long-Te
Jun 1, 2002·Journal of the American College of Cardiology·Menko-Jan de BoerUNKNOWN Zwolle Myocardial Infarction Study Group
Sep 19, 2003·Journal of the American College of Cardiology·Giuseppe De LucaUNKNOWN ZWOLLE Myocardial Infarction Study Group
Apr 20, 2004·Journal of the American College of Cardiology·Giuseppe De LucaHarry Suryapranata
Dec 27, 2005·The American Journal of Cardiology·Christina R RobinsonEllen C Keeley
Sep 11, 2012·Journal of the American College of Cardiology·Kristian ThygesenDaniel R Wagner
Sep 2, 2014·The New England Journal of Medicine·Gilles MontalescotUNKNOWN ATLANTIC Investigators
Jan 20, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Taishi YonetsuTsunekazu Kakuta

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