Pre-stroke dementia does not affect the post-acute care functional outcome of old patients with ischemic stroke

Geriatrics & Gerontology International
Eliyahu-Hayim MizrahiAbraham Adunsky

Abstract

The purpose of the present study was to evaluate whether a diagnosis of dementia before stroke onset (pre-stroke dementia [PSD]) affects the short-term functional outcome of elderly ischemic stroke patients. This was a retrospective case-control study comprising of consecutive elderly ischemic stroke patients. Functional outcome was assessed by the Functional Independence Measure scale (FIM) at admission and discharge. Data was analyzed by t-test, χ(2) -test, multiple linear regression analysis and logistic regression. There were 919 patients with acute ischemic stroke, out of whom 11.5% were diagnosed with PSD on index day. Compared with non-PSD patients, those with pre-stroke dementia had a shorter length of stay (P < 0.001), higher rate of female patients (P < 0.001) and lower Mini-Mental State Examination scores (P < 0.001). Both total and motor FIM scores at admission and discharge, and their respective FIM gain scores at discharge were higher in non-PSD compared with PSD patients (P < 0.001). In logistic regression analysis to identify factors predicting successful outcome (defined as total FIM at discharge ≥80), PSD remained as significantly associated with increased risk for adverse outcome on discharge (OR 2.449, CI 1....Continue Reading

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Citations

Sep 28, 2018·International Journal of Geriatric Psychiatry·Tobias MöllersHermann Brenner
Feb 12, 2019·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Amalie SaabGordon Bryan Young
Jan 9, 2021·Seminars in Neurology·Caitlin E D'SouzaJames F Meschia
Apr 13, 2021·Canadian Journal on Aging = La Revue Canadienne Du Vieillissement·Jonathan PlanteKenneth Rockwood

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