Abstract
Previous studies have shown that high cognitive ability, measured in childhood and prior to the experience of traumatic events, is protective of PTSD development. Our aim was to test if the association between pre-trauma verbal ability ascertained at 5 years with DSM-IV lifetime post-traumatic stress disorder (PTSD) at 21 years was subject to effect modification by gender, trauma type or prior behaviour problems. Using a prospective birth cohort of young Australians, we found that both trauma type and behaviour problems did not change the association between cognitive ability and PTSD. During multivariate analysis, testing for the interactive effect of gender revealed that verbal ability was linearly and inversely associated with PTSD in females only, with those in the lowest verbal ability quintile having strongly increased odds of PTSD (OR=3.89: 95% CI; 1.50, 10.10) compared with those in the highest quintile. A graph of the interaction revealed lower verbal ability placed females, but not males, at an increased risk of PTSD. Our results indicate that lower verbal ability in early childhood is a vulnerability factor for PTSD in females but not in males, and may constitute a gender-specific risk factor responsible for part of ...Continue Reading
References
Mar 1, 1989·British Journal of Obstetrics and Gynaecology·J D KeepingG M Williams
Dec 1, 1981·Psychological Reports·M J Breen
Dec 1, 1994·Perceptual and Motor Skills·J S ChildersS Wilson
Aug 1, 1993·Psychological Reports·D L JohnsonD Luttman
Jan 1, 1997·Der Nervenarzt
Dec 24, 1997·The Australian and New Zealand Journal of Psychiatry·W BorB C Behrens
May 16, 1998·Journal of Consulting and Clinical Psychology·M L MacklinR K Pitman
Sep 2, 1998·Psychological Medicine·L PetersF Carroll
Sep 3, 1999·Psychological Medicine·N BreslauV C Lucia
Apr 7, 2004·Archives of General Psychiatry·Stanley ZammitGlyn Lewis
Mar 3, 2005·Acta Psychiatrica Scandinavica·O FransM Fredrikson
Jun 14, 2005·International Journal of Epidemiology·J M NajmanG Shuttlewood
Jul 27, 2006·Journal of Abnormal Psychology·Mark W GilbertsonScott P Orr
Oct 21, 2006·Psychological Medicine·Karestan C KoenenAvshalom Caspi
Nov 8, 2006·Archives of General Psychiatry·Naomi BreslauGerman F Alvarado
Dec 19, 2006·Annals of Epidemiology·G David BattyLinda S Gottfredson
Jan 5, 2007·The American Journal of Psychiatry·Carla L StorrNaomi Breslau
Mar 7, 2007·Archives of General Psychiatry·William S KremenMichael J Lyons
Apr 3, 2007·Social Science & Medicine·Stephani L HatchMarcus Richards
May 9, 2007·Archives of General Psychiatry·William E CopelandE Jane Costello
Sep 14, 2007·Drug and Alcohol Dependence·Rosa AlatiGail M Williams
Dec 3, 2008·The American Journal of Psychiatry·Karestan C KoenenAvshalom Caspi
Dec 3, 2008·Archives of General Psychiatry·Catharine R GaleG David Batty
Feb 24, 2009·Epidemiology·G David BattyFinn Rasmussen
Jul 29, 2009·International Journal of Epidemiology·Rosa AlatiAlexandra Clavarino
Nov 7, 2009·Journal of the International Neuropsychological Society : JINS·Brian P MarxJennifer J Vasterling
Nov 13, 2009·Intelligence·Geoff DerIan J Deary
May 13, 2010·Psychological Medicine·B GlaserG Lewis
Aug 2, 2011·Journal of Anxiety Disorders·Kim Steven BettsRosa Alati