PMID: 6405024May 1, 1983Paper

Prealbumin as a biochemical marker of nutritional adequacy in premature infants

The Journal of Pediatrics
S R MoskowitzJ B Watkins

Abstract

To determine whether serum prealbumin would be useful in identifying adequacy of protein and calorie intake in premature infants, 17 infants between 26 and 33 weeks gestational age were studied throughout hospitalization. Serial anthropometric measurements, nutritional intake, and serum prealbumin concentrations were correlated. When mean intake of calories and protein was lower than 100 kcal/kg/day and less than 2 gm/kg/day, respectively, there was a significant difference in mean prealbumin values, compared with those in infants with a higher intake (P much less than 0.001). For infants with birth weights of 1000 gm or less, prealbumin correlated with protein intake (r = 0.66) and calorie intake (r = 0.64). In these infants, when protein intake exceeded 2 gm/kg/day, prealbumin concentrations increased to values reported for full-term infants in the first months of life. There was no significant correlation between intake of calories or protein and prealbumin values for infants born weighing greater than 1000 gm. Anthropometric measurements did not correlate with protein or calorie intake. We conclude that prealbumin is a sensitive measure of protein and calorie intake in premature infants, and that the definition of adequate ...Continue Reading

References

Mar 1, 1977·The Journal of Pediatrics·G E GaullC R Räihä
Jul 15, 1972·Lancet·Y IngenbleekP De Nayer
Jul 1, 1966·The Journal of Clinical Endocrinology and Metabolism·J H Oppenheimer, S C Werner
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Mar 1, 1969·Pediatric Research·M Winick, P Rosso
Dec 17, 1981·The New England Journal of Medicine·B ReichmanP R Swyer

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Citations

Apr 30, 1985·Clinica Chimica Acta; International Journal of Clinical Chemistry·F GulamaliP A Pleban
Apr 30, 1990·Clinica Chimica Acta; International Journal of Clinical Chemistry·M PressacY Ingenbleek
Jan 1, 1984·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·R L LochmillerW E Grant
Dec 1, 1985·The Journal of Pediatrics·W B PittardF C Rothstein
Jan 1, 1990·Journal of Pediatric & Perinatal Nutrition·J M Cox
Mar 1, 1996·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·M K Darby, J L Loughead
Oct 1, 1987·Acta Paediatrica Japonica; Overseas Edition·K W YenT Matsuo
Sep 2, 2009·Neonatal Network : NN·Patricia Nash
Dec 1, 1984·The Journal of Pediatrics·A G Philip
Jun 15, 1995·Analytical Chemistry·A M Spiekerman
Mar 1, 1988·JPEN. Journal of Parenteral and Enteral Nutrition·M R ThomasG M Chan
Nov 10, 2005·The Journal of Burn Care & Rehabilitation·Rungsinee A LiusuwanDavid G Greenhalgh
Sep 17, 2015·Advances in Nutrition·Yves Ingenbleek, Larry H Bernstein

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