Preanalytical mistakes in samples from primary care patients

Clinical Chemistry and Laboratory Medicine : CCLM
Adolfo RomeroManuel Muñoz

Abstract

Preanalytical mistakes (PAMs) in samples usually led to rejection upon arrival to the clinical laboratory. However, PAMs might not always be detected and result in clinical problems. Thus, PAMs should be minimized. We detected PAMs in samples from Primary Health Care Centres (PHCC) served by our central laboratory. Thus, the goal of this study was to describe the number and types of PAMs, and to suggest some strategies for improvement. The presence of PAMs, as sample rejection criteria, in samples submitted from PHCC to our laboratory during October and November 2007 was retrospectively analysed. Overall, 3885 PAMs (7.4%) were detected from 52,669 samples for blood analyses. This included missed samples (n=1763; 45.4% of all PAMs, 3.3% of all samples), haemolysed samples (n=1408; 36.2% and 2.7%, respectively), coagulated samples (n=391; 10% and 0.7%, respectively), incorrect sample volume (n=110; 2.8% and 0.2%, respectively), and others (n=213; 5.5% and 0.4%, respectively). For urine samples (n=18,852), 1567 of the samples were missing (8.3%). We found the proportion of PAMs in blood and urine samples to be 3-fold higher than that reported in the literature. Therefore, strategies for improvement directed towards the staff invol...Continue Reading

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Citations

Jan 15, 2015·Journal of Evidence-based Medicine·Hong Ying LiYu Lan
Aug 6, 2015·BMJ Quality & Safety·Ian LitchfieldSheila Greenfield
Oct 4, 2011·Clinica Chimica Acta; International Journal of Clinical Chemistry·Adolfo RomeroManuel Muñoz
Nov 28, 2013·Clinical Chemistry and Laboratory Medicine : CCLM·Juan Gómez-SalgadoCarlos Ruiz-Frutos
May 23, 2020·International Journal of Environmental Research and Public Health·Adolfo Romero-AranaAdolfo Romero

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