PMID: 2420393Mar 1, 1986

Precipitating monoclonal antibodies to 1 of the antigenic determinants of streptococcal group-A polysaccharide

Biulleten' eksperimental'noĭ biologii i meditsiny
E I DrobyshevskaiaI M Liampert

Abstract

Monoclonal antibodies (MCA) to streptococcal group A polysaccharide (A-PS) were prepared. Precipitating MCA are directed to the determinant common for A-PS and streptococcal group L polysaccharide (L-PS). The antibodies react in the immunodiffusion test and give identity reaction in A- and L-PS tests. Other MCA are non-precipitating but react with A-PS studied by immunoenzyme method. The reasons for the formation of precipitating and non-precipitating MCA to different antigenic determinants of A-PS are discussed.

Citations

Jan 1, 1989·Biulleten' eksperimental'noĭ biologii i meditsiny·E I DrobyshevskaiaL V Beletskaia
Jun 1, 1988·Biulleten' eksperimental'noĭ biologii i meditsiny·E I DrobyshevskaiaV Iu Sanina

Related Concepts

Monoclonal Antibodies
Antigenic Specificity
Immunodiffusion Measurement
Hybridomas
Variolation
Peroxidase-Antiperoxidase Complex Technique
Mice, Inbred BALB C
Polysaccharides, Bacterial
Precipitin Tests
Bacteria, Flesh-Eating

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