PMID: 2488150Feb 1, 1989Paper

Precise measurement of vertebral bone density using computed tomography without the use of an external reference phantom

Journal of Digital Imaging
S D BodenR M Allman

Abstract

Bone density measurement by quantitative computed tomography (QCT) commonly uses an external reference phantom to decrease scan-to-scan and scanner-to-scanner variability. However, the peripheral location of these phantoms and other phantom variables is also responsible for a measurable degradation in accuracy and precision. Due to non-uniform artifacts such as beam hardening, scatter, and volume averaging, the ideal reference phantom should be as close to the target tissue as possible. This investigation developed and tested a computer program that uses paraspinal muscle and fat tissue as internal reference standards in an effort to eliminate the need for an external phantom. Because of their proximity, these internal reference tissues can be assumed to reflect more accurately the local changes in the x-ray spectra and scatter distribution at the target tissue. A user interactive computerized histogram plotting technique enabled the derivation of reproducible CT numbers for muscle, fat, and trabecular bone. Preliminary results indicate that the use of internal reference tissues with the histogram technique may improve reproducibility of scan-to-scan measurements as well as inter-scanner precision. Reproducibility studies on 16...Continue Reading

References

Nov 1, 1978·Medical Physics·D R White
Jan 1, 1976·Neuroradiology·R A RutherfordI Isherwood
Oct 1, 1987·Calcified Tissue International·H K GenantS T Harris
Jan 1, 1986·Physics in Medicine and Biology·R B Merritt, S G Chenery
Jan 22, 1987·The New England Journal of Medicine·F M HallD T Baran
Mar 1, 1987·Investigative Radiology·M M GoodsittJ Coumas
Aug 1, 1987·Radiology·W A KalenderC Suess
May 1, 1986·Radiology·A M Laval-JeantetR B Mazess
May 1, 1983·The British Journal of Radiology·E Breatnach, P J Robinson
Aug 1, 1980·Journal of Computer Assisted Tomography·C E Cann, H K Genant
May 1, 1980·Medical Physics·G H Glover, N J Pelc

❮ Previous
Next ❯

Citations

Mar 1, 1993·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·H GudmundsdottirG Sigurdsson
Mar 30, 2007·Archives of Orthopaedic and Trauma Surgery·Rene BurchardMarkus Lengsfeld
Jan 25, 2013·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Joshua D EvansJeffrey F Williamson
Apr 8, 2011·American Journal of Respiratory and Critical Care Medicine·Naoya TanabeMichiaki Mishima
Dec 20, 2011·Climacteric : the Journal of the International Menopause Society·Y MiyabaraA E Kearns
Dec 1, 1993·Arthritis and Rheumatism·M Jergas, H K Genant
Sep 11, 2012·Academic Radiology·Wei-Liang TayAlvin Choong-Meng Ng
Mar 13, 2010·European Journal of Radiology·Dirk K MuellerJoachim Erckenbrecht
Apr 30, 2008·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Klaus EngelkeE Michael Lewiecki
Jun 14, 2012·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Elisabeth A P M RommeWilliam Macnee
May 19, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Perry J PickhardtNeil Binkley
Apr 27, 2000·IEEE Transactions on Medical Imaging·C H YanS Napel
Jun 2, 2014·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Perry PickhardtNeil Binkley
Aug 19, 2015·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Klaus EngelkeJohn T Shousboe
May 31, 2018·Current Osteoporosis Reports·Fjola JohannesdottirMary L Bouxsein
Mar 7, 2018·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Florieke EggermontEsther Tanck
Apr 11, 2008·Respirology : Official Journal of the Asian Pacific Society of Respirology·Tadashi OharaMichiaki Mishima
Nov 16, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M T LöfflerT Baum
Dec 6, 2000·Journal of Computer Assisted Tomography·K D HopperA R Kunselman
Feb 16, 2020·Medical Engineering & Physics·Andrew S MichalskiSteven K Boyd

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.