Precise visuotopic organization of the blind spot representation in primate V1

Journal of Neurophysiology
João C B AzziMario Fiorani

Abstract

The optic disk is a region of the retina consisting mainly of ganglion cell axons and blood vessels, which generates a visual scotoma known as the blind spot (BS). Information present in the surroundings of the BS can be used to complete the missing information. However, the neuronal mechanisms underlying these perceptual phenomena are poorly understood. We investigate the topography of the BS representation (BSR) in cortical area V1 of the capuchin monkey, using single and multiple electrodes. Receptive fields (RFs) of neurons inside the BSR were investigated using two distinct automatic bias-free mapping methods. The first method (local mapping) consisted of randomly flashing small white squares. For the second mapping method (global mapping), we used a single long bar that moved in one of eight directions. The latter stimulus was capable of eliciting neuronal activity inside the BSR, possibly attributable to long-range surround activity taking place outside the borders of the BSR. Importantly, we found that the neuronal activity inside the BSR is organized topographically in a manner similar to that found in other portions of V1. On average, the RFs inside the BS were larger than those outside. However, no differences in ori...Continue Reading

References

Oct 1, 1992·Journal of Neurophysiology·J H Maunsell, J R Gibson
Sep 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·M W Pettet, C D Gilbert
Sep 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·M Fiorani JúniorC E Rocha-Miranda
Mar 12, 1992·Nature·C D Gilbert, T N Wiesel
Sep 26, 1991·Nature·P R Andrews, F W Campbell
Jul 24, 1989·Brain Research·S E RaiguelG A Orban
Jan 1, 1988·Experimental Brain Research·M G RosaM Fiorani Júnior
May 22, 1987·The Journal of Comparative Neurology·R GattassM G Rosa
Dec 1, 1974·The Journal of Comparative Neurology·D H Hubel, T N Wiesel
Mar 1, 1968·The Journal of Physiology·D H Hubel, T N Wiesel
Jan 1, 1984·Vision Research·J C Letelier, F Varela
Jan 1, 1981·Experimental Brain Research·B M DowR Bauer
Mar 1, 1995·Visual Neuroscience·S P TripathyC Harden
Jan 23, 1996·Proceedings of the National Academy of Sciences of the United States of America·C D GilbertG Westheimer
Jan 1, 1995·Perception·F H DurginD M Levi
Jun 1, 1996·Vision Research·S P TripathyH Ogmen
Dec 1, 1996·Brain Research. Cognitive Brain Research·H KomatsuM Kinoshita
Aug 1, 1998·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·A K Amorim, C W Picanço-Diniz
Nov 14, 1998·Brain Research. Brain Research Protocols·P BuzásZ F Kisvárday
Oct 16, 1999·Proceedings of the National Academy of Sciences of the United States of America·M K KapadiaC D Gilbert
Nov 14, 2000·Journal of Neuroscience Methods·Z F KisvárdayU T Eysel
Aug 9, 2001·The Journal of Comparative Neurology·P BuzásZ F Kisvárday
Oct 19, 2002·Science·Daniel L Adams, Jonathan C Horton
Dec 7, 2002·Neuron·Shaul Hochstein, Merav Ahissar
Oct 14, 2004·Clinical and Experimental Pharmacology & Physiology·J G M SoaresR Gattass
Jan 7, 2005·Journal of Neurophysiology·Masayuki Matsumoto, Hidehiko Komatsu
Feb 25, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Amir ShmuelAmiram Grinvald
Jun 7, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Ricardo GattassMario Fiorani
Jul 22, 2005·Journal of Neurophysiology·Holger AwaterFrank Tong
Sep 28, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Daniel L AdamsJonathan C Horton
Apr 3, 2012·Experimental Neurology·Ana Karla Jansen-AmorimRicardo Gattass

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Citations

Dec 14, 2016·Vision Research·Jamie K Opper, Vicki J Volbrecht

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