Precisely Determining Ultralow level UO2(2+) in Natural Water with Plasmonic Nanowire Interstice Sensor

Scientific Reports
Raekeun GwakBongsoo Kim

Abstract

Uranium is an essential raw material in nuclear energy generation; however, its use raises concerns about the possibility of severe damage to human health and the natural environment. In this work, we report an ultrasensitive uranyl ion (UO2(2+)) detection method in natural water that uses a plasmonic nanowire interstice (PNI) sensor combined with a DNAzyme-cleaved reaction. UO2(2+) induces the cleavage of DNAzymes into enzyme strands and released strands, which include Raman-active molecules. A PNI sensor can capture the released strands, providing strong surface-enhanced Raman scattering signal. The combination of a PNI sensor and a DNAzyme-cleaved reaction significantly improves the UO2(2+) detection performance, resulting in a detection limit of 1 pM and high selectivity. More importantly, the PNI sensor operates perfectly, even in UO2(2+)-contaminated natural water samples. This suggests the potential usefulness of a PNI sensor in practical UO2(2+)-sensing applications. We anticipate that diverse toxic metal ions can be detected by applying various ion-specific DNA-based ligands to PNI sensors.

References

Jun 19, 2004·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Elena CraftMohamed Abou-Donia
Jun 28, 2005·Nucleic Acids Research·Nicholas R Markham, Michael Zuker
Feb 8, 2007·Proceedings of the National Academy of Sciences of the United States of America·Juewen LiuYi Lu
Dec 10, 2008·Journal of the American Chemical Society·Ted A LaurenceThomas Huser
Dec 23, 2008·Journal of the American Chemical Society·Ilsun YoonBongsoo Kim
Jan 15, 2009·Chembiochem : a European Journal of Chemical Biology·Andrea K BrownYi Lu
Feb 5, 2011·Chemistry : a European Journal·Taejoon KangBongsoo Kim
Apr 13, 2011·Nanotechnology·Myeong-Lok SeolYang-Kyu Choi
Nov 9, 2011·Analytical and Bioanalytical Chemistry·Robert ZiółkowskiElżbieta Malinowska
Feb 11, 2012·Nanotechnology·Myeong-Lok SeolYang-Kyu Choi
Oct 9, 2012·Physical Chemistry Chemical Physics : PCCP·Samuel L KleinmanRichard P Van Duyne
Mar 28, 2013·Journal of the American Chemical Society·Peiwen WuYi Lu
Apr 16, 2013·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Bin ZhouJia-Cheng Wang
Nov 26, 2013·Chemistry, an Asian Journal·Hongki KimBongsoo Kim
Oct 14, 2014·Biosensors & Bioelectronics·Eunsu ChungJaebum Choo

❮ Previous
Next ❯

Citations

Dec 21, 2019·Nanoscale·Roger M Pallares, Rebecca J Abergel
Aug 25, 2018·Frontiers in Chemistry·Sepehr ManochehryYingfu Li
Nov 28, 2020·Analytical Chemistry·Joshua M ZieglerReginald M Penner
Apr 20, 2021·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Xiaoyan CaoHuiping Guo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.