Precision Medicine in Rhinosinusitis

Current Allergy and Asthma Reports
I M VlastosE P Prokopakis

Abstract

Our scope is the presentation of research and clinical progresses in relation to precision medicine that are expected to alter our clinical practice in relation to chronic rhinosinusitis (CRS). Current knowledge on phenotypes and endotypes, biomarkers, and clinical markers for diagnosis, medical and surgical therapy, and prognosis is presented as well as the role of precision medicine in United Airway Disease and SCUAD (severe-uncontrolled chronic upper airway inflammation). Current technological progresses, mostly in relation to molecular biology and information technology, have permitted more detailed pathophysiological assessments and multidimensional approaches in airways diseases. Based on the concept of united airways diseases, new classification schemes, called endotypes, have been proposed for CRS. In addition, novel biological treatments that have been introduced for the treatment of asthma show great promise as well for severe uncontrolled cases of CRS with nasal polyps. Central to this approach are new biomarkers that are being examined in relation to complex bio-clinical traits of CRS. As this narrative review of the aforementioned precision medicine initiatives in relation to CRS advances, a modification of current...Continue Reading

References

Nov 27, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jeong-Whun KimChae-Seo Rhee
Aug 8, 2009·The Journal of Allergy and Clinical Immunology·Jean BousquetUNKNOWN Extended Global Allergy and Asthma European Network, World Allergy Organization and Allergic Rhinitis and its Impact on Asth
Mar 31, 2012·The Journal of Allergy and Clinical Immunology·Weiping WenUNKNOWN Nasal Health Group, China (NHGC)
Oct 2, 2012·The Journal of Allergy and Clinical Immunology·Philippe GevaertClaus Bachert
Dec 12, 2012·Current Opinion in Allergy and Clinical Immunology·Emmanuel ProkopakisBerrylin J Ferguson
Mar 9, 2013·American Journal of Respiratory and Critical Care Medicine·Nicola A HananiaWilliam Busse
Feb 22, 2014·Current Allergy and Asthma Reports·Christos GeorgalasWytske Fokkens
Oct 10, 2014·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·K J BainesP G Gibson
Dec 9, 2014·The Journal of Allergy and Clinical Immunology·Chengshuo WangLuo Zhang
Jan 13, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael S BenningerClaire Hopkins
Feb 20, 2015·International Forum of Allergy & Rhinology·Zachary M SolerRodney J Schlosser
Mar 3, 2015·The Journal of Allergy and Clinical Immunology·Hyun-Woo ShinDae Woo Kim
Nov 26, 2015·The World Allergy Organization Journal·G W CanonicaJ Bousquet
Dec 15, 2015·The Journal of Allergy and Clinical Immunology·Claus BachertPhillippe Gevaert
Mar 2, 2016·Annals of Internal Medicine·Wylie Burke, Susan Brown Trinidad
Mar 8, 2016·The Journal of Allergy and Clinical Immunology·Peter TomassenClaus Bachert
Mar 13, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Claus Bachert, Daniel L Hamilos
Apr 16, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Rohit DivekarJoseph Butterfield
Jul 10, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Claus Bachert, Cezmi A Akdis
Dec 6, 2016·Laryngoscope Investigative Otolaryngology·Steven K DennisAmber Luong
Feb 25, 2017·Current Allergy and Asthma Reports·Alexander KaratzanisEmmanuel Prokopakis
May 13, 2017·Allergy, Asthma & Immunology Research·Dae Woo Kim, Seong H Cho
Jul 15, 2017·Clinical and Translational Allergy·Glynnis De GreveSven F Seys
Aug 26, 2017·Cell·Ali TorkamaniEric J Topol
Oct 21, 2017·The European Respiratory Journal·Alvar AgustíUNKNOWN on behalf of all participants in the seminar
Mar 27, 2018·Current Allergy and Asthma Reports·Klementina Avdeeva, Wytske Fokkens
May 8, 2018·The Journal of Allergy and Clinical Immunology·Claus BachertJean Bousquet
Jul 11, 2018·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Wytske J FokkensPeter W Hellings
Oct 3, 2018·The Journal of Allergy and Clinical Immunology·Jean BousquetUNKNOWN Mobile Airways Sentinel Network (MASK) Study Group

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Citations

May 29, 2019·Current Opinion in Allergy and Clinical Immunology·Enrico HefflerGiorgio Walter Canonica
Feb 11, 2020·Italian Journal of Pediatrics·Attilio VarricchioGiorgio Ciprandi
Apr 2, 2021·Current Allergy and Asthma Reports·Ioannis VlastosEmmanuel Prokopakis
Aug 8, 2021·Journal of Clinical Medicine·Kamil RadajewskiPaweł Burduk

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