Precision of distances and ordering of microsatellite markers in consensus linkage maps of chromosomes 1, 3 and 4 from two reciprocal chicken populations using bootstrap sampling

Genetics and Molecular Research : GMR
M F RosárioA A F Garcia

Abstract

Some factors complicate comparisons between linkage maps from different studies. This problem can be resolved if measures of precision, such as confidence intervals and frequency distributions, are associated with markers. We examined the precision of distances and ordering of microsatellite markers in the consensus linkage maps of chromosomes 1, 3 and 4 from two F(2) reciprocal Brazilian chicken populations, using bootstrap sampling. Single and consensus maps were constructed. The consensus map was compared with the International Consensus Linkage Map and with the whole genome sequence. Some loci showed segregation distortion and missing data, but this did not affect the analyses negatively. Several inversions and position shifts were detected, based on 95% confidence intervals and frequency distributions of loci. Some discrepancies in distances between loci and in ordering were due to chance, whereas others could be attributed to other effects, including reciprocal crosses, sampling error of the founder animals from the two populations, F(2) population structure, number of and distance between microsatellite markers, number of informative meioses, loci segregation patterns, and sex. In the Brazilian consensus GGA1, locus LEI1...Continue Reading

References

Jul 1, 1992·Genomics·N Bumstead, J Palyga
Mar 1, 1994·The Journal of Heredity·I LevinJ B Dodgson
May 23, 1998·Genomics·M A GroenenJ J van der Poel
Aug 7, 1999·Human Heredity·J Halpern, A S Whittemore
Dec 7, 2000·Genetic Epidemiology·E W DawE M Wijsman
Dec 22, 2000·Cytogenetics and Cell Genetics·M SchmidS Mizuno
May 16, 2002·The Journal of Heredity·R E Voorrips
Aug 10, 2002·Bioinformatics·M Fishelson, D Geiger
Dec 6, 2003·Genome Research·Chengwei RenHong-Bin Zhang
Feb 19, 2004·Cytogenetic and Genome Research·J AertsM Groenen
Dec 14, 2004·Nature·UNKNOWN International Chicken Genome Sequencing Consortium
Dec 14, 2004·Nature·Gane Ka-Shu WongUNKNOWN International Chicken Polymorphism Map Consortium
Dec 14, 2004·Nature·John W WallisWesley C Warren
Dec 21, 2004·Nucleic Acids Research·Jing WangJun Wang
May 21, 2005·Cytogenetic and Genome Research·M SchmidS Mizuno
Jun 10, 2005·BMC Genomics·Warren M SnellingTimothy P L Smith
Oct 1, 2005·Genetics, Selection, Evolution : GSE·Danyel G J JennenMartien A M Groenen
Sep 21, 2006·Biometrics·William C L Stewart, Elizabeth A Thompson
Dec 1, 2006·Poultry Science·B AbashtS J Lamont
Nov 9, 2007·Genome Research·Tara C MatiseSteven Buyske
May 27, 2009·Animal Genetics·R L R CamposL L Coutinho
Jul 30, 2009·Heredity·M MollinariA A F Garcia
Nov 1, 1992·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·A Darvasi, M Soller

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