PMID: 8593712Sep 1, 1995Paper

Precision of laser Doppler scanning in clinical use

Clinical and Experimental Dermatology
M StückerP Altmeyer

Abstract

Reactions of the cutaneous microcirculation to local stimuli have been quantitated in terms of area of erythema (planimetry), change in colour (colorimetry) and time-dependent changes in perfusion (one-dimensional laser Doppler fluxmetry (LDF)). Using the new technique of laser Doppler scanning (LDS) it is now possible to quantify and demonstrate two-dimensional patterns of microvascular perfusion in terms of intensity and extent. The precision of this new technique was compared with the previously established techniques by examining the reactions of 15 healthy volunteers to the intracutaneous injection of carbacholin and isotonic NaCl solutions. Both stimuli were applied paravertebrally, on the left and right side. Reactions were examined after 10 min. As a control for temporal reproducibility the examination was repeated on another day. All methods allowed the differentiation of reactions to carbacholin from those to NaCl (P < or = 0.0001). Only colorimetry and LDS provided data that were unequivocally reproducible when comparing both sides (r > or = 0.78). Using LDF or planimetry, reproducibility of values was lower (r < or = 0.58). When looking at measurements performed on different days, only values of LDS were reproducibl...Continue Reading

References

Apr 27, 1977·Archives of Dermatological Research·P Altmeyer
Jul 1, 1991·The British Journal of Dermatology·A G QuinnP M Farr
Sep 1, 1990·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·C Iadecola, D J Reis
Jan 1, 1980·IEEE Transactions on Bio-medical Engineering·G E NilssonP A Obert
Jan 1, 1994·Dermatology : International Journal for Clinical and Investigative Dermatology·K HoffmannP Altmeyer
Apr 1, 1993·IEEE Transactions on Bio-medical Engineering·K WårdellG E Nilsson
May 1, 1993·Medical & Biological Engineering & Computing·A Jakobsson, G E Nilsson
May 1, 1993·The British Journal of Dermatology·E L SpeightP M Farr

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Citations

Dec 17, 2003·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J SaravanamuthuA B Maclean
Nov 1, 2000·Critical Care : the Official Journal of the Critical Care Forum·N H BoyleR C Mason
Mar 25, 2004·Wiener klinische Wochenschrift·Franz Kainberger, Sepp Leodolter
Oct 2, 2007·Explore : the Journal of Science and Healing·Arya NielsenTed J Kaptchuk
Mar 17, 2012·The Journal of Pharmacy and Pharmacology·Stephanie Li Mei TayLai Wah Chan
May 4, 2005·The International Journal of Lower Extremity Wounds·Faisel Khan, David J Newton
Apr 7, 2007·American Journal of Physical Medicine & Rehabilitation·Charles F KunkelA M Erika Scremin
Jun 15, 2005·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Ahmad Y SheikhThomas K Hunt
Apr 2, 2010·American Journal of Physical Medicine & Rehabilitation·Oscar U ScreminMark Mandelkern
Jan 25, 2008·Dermatology : International Journal for Clinical and Investigative Dermatology·F G BecharaP Altmeyer
Oct 1, 1996·Journal of Clinical Laser Medicine & Surgery
Oct 22, 2008·Scandinavian Journal of Gastroenterology·William KempHenry Krum

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