Precision of recombination frequency estimates after random intermating with finite population sizes.

Genetics
Matthias Frisch, Albrecht E Melchinger

Abstract

Random intermating of F2 populations has been suggested for obtaining precise estimates of recombination frequencies between tightly linked loci. In a simulation study, sampling effects due to small population sizes in the intermating generations were found to abolish the advantages of random intermating that were reported in previous theoretical studies considering an infinite population size. We propose a mating scheme for intermating with planned crosses that yields more precise estimates than those under random intermating.

References

May 10, 2002·Plant Molecular Biology·Michael LeeArnel Hallauer
Feb 21, 2006·Genetics·Olivier C Martin, Frédéric Hospital
Jul 13, 2006·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·K C FalkeM Frisch

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Citations

Aug 16, 2012·Genetics Research·Ziqi SunJiankang Wang
Mar 14, 2009·PLoS Genetics·Matthew V Rockman, Leonid Kruglyak

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