PMID: 9535142Apr 16, 1998Paper

Preclinical changes of extracoronary arterial structures as indicators of coronary atherosclerosis in men

Journal of Hypertension
J L MegnienJ Levenson

Abstract

Carotid artery structure change was associated with coronary artery stenosis by angiography of subjects who were for the most part symptomatic. To determine whether structural changes at multiple extracoronary sites were associated with noninvasively detected coronary calcium for 94 asymptomatic high-risk men. B-mode ultrasonography allowed us to detect plaque at three sites (carotid, femoral, and abdominal aorta) and to measure intima-medial thickness both in common carotid and in femoral arteries. Ultrafast computed tomography determined the presence and amount of coronary calcification. After adjustment for age, plaques at two or three sites were associated with extensive amounts of coronary calcium [odds ratio 4.94 (95% confidence interval 1.08-23)], but not with the presence of coronary calcium; increase in carotid intima-medial thickness was not associated with presence and extent of coronary calcium; and increase in femoral intima-medial thickness was associated with presence of coronary calcium [odds ratio 1.44 (95% confidence interval 1.03-2)] and extensive coronary calcium [odds ratio 1.50 (95% confidence interval 0.97-2.33)]. Adjustment for cardiovascular risk factors attenuated these associations. Femoral intima-med...Continue Reading

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Citations

May 23, 2001·Ultrasound in Medicine & Biology·K J HuntG Heiss
Dec 19, 2008·Current Cardiology Reports·Stein Harald Johnsen, Ellisiv B Mathiesen
Aug 18, 2009·Journal of the Neurological Sciences·Sándor MolnárLászló Csiba
Jun 24, 2008·Pathophysiology : the Official Journal of the International Society for Pathophysiology·Phoebe A StapletonJefferson C Frisbee
Mar 7, 2002·The American Journal of Cardiology·J David Spence
Apr 10, 2016·Chinese Journal of Integrative Medicine·Chi ZhangAi-ping Lu
Feb 16, 2010·Atherosclerosis·Yasmin S HamiraniMatthew J Budoff
Feb 26, 2015·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yan ZhangWayne W Zhang
Dec 7, 2002·Stroke; a Journal of Cerebral Circulation·J David SpenceTara Lohmann
Mar 27, 2004·Stroke; a Journal of Cerebral Circulation·J David Spence
Nov 6, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·J David Spence, Robert A Hegele
Aug 15, 2009·Arteriosclerosis, Thrombosis, and Vascular Biology·Aloke V FinnRenu Virmani

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