Preclinical methodological approaches investigating of the effects of alcohol on perinatal and adolescent neurodevelopment.

Neuroscience and Biobehavioral Reviews
Craig D C BaileyCheryl M McCormick

Abstract

Despite much evidence of its economic and social costs, alcohol use continues to increase. Much remains to be known as to the effects of alcohol on neurodevelopment across the lifespan and in both sexes. We provide a comprehensive overview of the methodological approaches to ethanol administration when using animal models (primarily rodent models) and their translational relevance, as well as some of the advantages and disadvantages of each approach. Special consideration is given to early developmental periods (prenatal through adolescence), as well as to the types of research questions that are best addressed by specific methodologies. The zebrafish is used increasingly in alcohol research, and how to use this model effectively as a preclinical model is reviewed as well.

References

Mar 1, 1979·Early Human Development·J Dobbing, J Sands
Feb 1, 1979·Pharmacology, Biochemistry, and Behavior·E P RileyJ Baldwin
Jun 1, 1992·Pediatric Research·C A Gleason, K J Hotchkiss
Oct 1, 1990·Alcoholism, Clinical and Experimental Research·S K ClarrenW J Shoemaker
Jan 31, 1991·Behavioural Brain Research·B ZimmerbergJ D Stekler
Jan 1, 1987·Journal of Substance Abuse Treatment·N S MillerM S Gold
Apr 1, 1980·Alcoholism, Clinical and Experimental Research·J D DexterC C Middleton
Jul 1, 1995·Developmental Dynamics : an Official Publication of the American Association of Anatomists·C B KimmelT F Schilling
Sep 1, 1996·Alcoholism, Clinical and Experimental Research·F E LancasterS B Wren
Apr 17, 1998·Drug and Alcohol Dependence·D B ClarkR E Tarter
Apr 12, 2000·Neurotoxicology and Teratology·J Spear-SmithJ D Reynolds
May 19, 2000·Neuroscience and Biobehavioral Reviews·L P Spear
Feb 13, 2001·Pharmacology, Biochemistry, and Behavior·R GerlaiA Rosenthal
Aug 3, 2001·Neuroscience·B ClancyB L Finlay
Dec 6, 2001·Nature Reviews. Genetics·E E Patton, L I Zon
Sep 11, 2002·Trends in Neurosciences·Robert Gerlai
May 7, 2003·Neuroscience and Biobehavioral Reviews·Susan L Andersen
May 22, 2003·Neurotoxicology and Teratology·Michelle L ByrnesJames F Brien
May 31, 2003·Canadian Journal of Physiology and Pharmacology·Tara N McGoeyJames F Brien
Sep 16, 2003·Neurotoxicology and Teratology·Tuan D Tran, Sandra J Kelly
Dec 11, 2003·JAMA : the Journal of the American Medical Association·Robert J SokolBeth Nordstrom
Mar 10, 2004·Journal of Neurobiology·Ethan Gahtan, Herwig Baier
Mar 17, 2004·Neurotoxicology and Teratology·A D RobertsM L Schneider
Jun 29, 2004·Nature Neuroscience·Ian C G WeaverMichael J Meaney
Sep 29, 2004·Neurotoxicology and Teratology·Michael J CarvanFrederick E Williams
Dec 15, 2004·Alcoholism, Clinical and Experimental Research·Sang Soo KangCatherine Rivier
Jul 28, 2005·Alcoholism, Clinical and Experimental Research·Sören SiegmundRainer Spanagel
Sep 15, 2005·American Journal of Obstetrics and Gynecology·M EndresC Y Spong
Oct 6, 2005·Alcoholism, Clinical and Experimental Research·Steven C Brunell, Linda P Spear
Nov 5, 2005·Alcoholism, Clinical and Experimental Research·Tamara L DoremusLinda P Spear
Jan 26, 2006·Alcoholism, Clinical and Experimental Research·Michael E NizhnikovNorman E Spear
Jun 7, 2006·Physiology & Behavior·Hadley C BergstromRobert F Smith

❮ Previous
Next ❯

Citations

Aug 8, 2021·Progress in Neuro-psychopharmacology & Biological Psychiatry·Amira AbozaidRobert Gerlai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Alcoholism, Clinical and Experimental Research
Lindsay M SquegliaDouglas B Matthews
Pharmacology, Biochemistry, and Behavior
Briana LeesLindsay M Squeglia
Current Opinion in Neurobiology
Joseph G Gleeson, Franck Polleux
Alcoholism, Clinical and Experimental Research
Duncan B ClarkSusan F Tapert
The American Journal of Drug and Alcohol Abuse
Monica LucianaKelvin O Lim
© 2021 Meta ULC. All rights reserved