Preconditioning of skeletal muscle against contraction-induced damage: the role of adaptations to oxidants in mice

The Journal of Physiology
F McArdleM J Jackson

Abstract

Adaptations of skeletal muscle following exercise are accompanied by changes in gene expression, which can result in protection against subsequent potentially damaging exercise. One cellular signal activating these adaptations may be an increased production of reactive oxygen and nitrogen species (ROS). The aim of this study was to examine the effect of a short period of non-damaging contractions on the subsequent susceptibility of muscle to contraction-induced damage and to examine the changes in gene expression that occur following the initial contraction protocol. Comparisons with changes in gene expression in cultured myotubes following treatment with a non-damaging concentration of hydrogen peroxide (H(2)O(2)) were used to identify redox-sensitive genes whose expression may be modified by the increased ROS production during contractions. Hindlimb muscles of mice were subjected to a preconditioning, non-damaging isometric contraction protocol in vivo. After 4 or 12 h, extensor digitorum longus (EDL) and soleus muscles were removed and subjected to a (normally) damaging contraction protocol in vitro. Muscles were also analysed for changes in gene expression induced by the preconditioning protocol using cDNA expression techni...Continue Reading

References

Nov 1, 1992·Journal of Applied Physiology·M B ReidM L Entman
Dec 16, 1991·Clinica Chimica Acta; International Journal of Clinical Chemistry·J A West-JordanM J Jackson
Nov 20, 1985·Biochimica Et Biophysica Acta·M J JacksonM C Symons
Oct 1, 1987·Journal of Applied Physiology·D J NewhamP M Clarkson
Nov 20, 1986·Journal of Immunological Methods·D Gerlier, N Thomasset
May 1, 1985·Journal of Gerontology·M HiguchiJ O Holloszy
Aug 31, 1982·Biochemical and Biophysical Research Communications·K J DaviesL Packer
Mar 1, 1984·Clinical Science·D A JonesR H Edwards
Oct 1, 1984·European Journal of Clinical Investigation·M J JacksonR H Edwards
Feb 1, 1984·International Journal of Sports Medicine·R R JenkinsH Howald
Apr 1, 1995·Archives of Biochemistry and Biophysics·A G WieseK J Davies
Dec 1, 1994·Journal of Applied Physiology·T W Balon, J L Nadler
Feb 1, 1993·Medicine and Science in Sports and Exercise·L L Ji
Aug 16, 1996·The Journal of Biological Chemistry·H M LanderJ M Tauras
Aug 1, 1996·Biochemical Society Transactions·A McArdle, M J Jackson
Sep 1, 1996·Journal of Applied Physiology·C A O'NeillJ C Longhurst
Jan 1, 1997·Annual Review of Immunology·H NakamuraJ Yodoi
Aug 5, 1998·Journal of Molecular and Cellular Cardiology·S V TortiF M Torti
Sep 23, 2000·American Journal of Physiology. Endocrinology and Metabolism·H PilegaardP D Neufer
Oct 18, 2000·Free Radical Biology & Medicine·E Cadenas, K J Davies
Dec 20, 2000·The Journal of Clinical Investigation·T MatobaA Takeshita
Feb 15, 2001·American Journal of Physiology. Cell Physiology·A McArdleM J Jackson
Feb 24, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·R A MillerR J Shmookler-Reis
Jun 19, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·T J Koh, S V Brooks
Jun 25, 2002·Molecular Aspects of Medicine·Malcolm J JacksonSiân B Astley
Jul 2, 2002·American Journal of Respiratory Cell and Molecular Biology·Danielle Morse, Augustine M K Choi
Jul 13, 2002·American Journal of Physiology. Lung Cellular and Molecular Physiology·Esther BarreiroSabah N A Hussain
Dec 5, 2002·The Journal of Bone and Joint Surgery. British Volume·Alison J BushellMalcolm J Jackson

❮ Previous
Next ❯

Citations

Mar 31, 2006·European Journal of Applied Physiology·Alessandra FerriMichel Pousson
Nov 8, 2006·European Journal of Applied Physiology·K NosakaP B Laursen
Mar 17, 2010·European Journal of Applied Physiology·Lee TaylorLars R McNaughton
May 26, 2011·European Journal of Applied Physiology·Hsin-Lian ChenTrevor C Chen
Jun 17, 2010·Amino Acids·Lee TaylorLars R McNaughton
May 17, 2012·Cell Stress & Chaperones·Chad D TouchberryPhilip M Gallagher
Jun 28, 2011·Antioxidants & Redox Signaling·Malcolm J Jackson
Sep 22, 2007·Critical Care Medicine·Thomas BongersAnne McArdle
Feb 6, 2010·Critical Care Medicine·Adam LightfootRichard D Griffiths
Feb 6, 2010·Critical Care Medicine·Malcolm J Jackson
Dec 3, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Malcolm J Jackson
May 12, 2012·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Hsin-Lian ChenTrevor C Chen
Jun 8, 2006·Annual Review of Biochemistry·Deborah M Muoio, Christopher B Newgard
Oct 17, 2008·Physiological Reviews·Scott K Powers, Malcolm J Jackson
Oct 15, 2013·Canadian Journal of Physiology and Pharmacology·Rosario SolisJorge A Sánchez
Dec 21, 2010·Free Radical Biology & Medicine·Scott K PowersMatthew B Hudson
Sep 15, 2009·Free Radical Biology & Medicine·Malcolm J Jackson
Aug 21, 2007·Journal of Science and Medicine in Sport·Andrew P Lavender, Kazunori Nosaka
Nov 25, 2006·Experimental Cell Research·Jon P GoldingJonathan R Beauchamp
Jul 17, 2008·IUBMB Life·Malcolm J Jackson
Oct 27, 2010·Scandinavian Journal of Medicine & Science in Sports·P G GandraD V Macedo
Nov 3, 2009·Experimental Physiology·Scott K PowersErin E Talbert
Sep 26, 2006·Mechanisms of Ageing and Development·A VasilakiA McArdle
Jan 29, 2016·Redox Report : Communications in Free Radical Research·Aleksandra Nikolić-KokićVidosava Rakočević-Stojanović
Sep 3, 2013·Free Radical Research·S Ben-ZakenY Meckel
Jun 14, 2015·Clinical Orthopaedics and Related Research·Heather-Marie P WilsonMargaret D Allen
Apr 14, 2015·Biomolecules·Peter Steinbacher, Peter Eckl
Dec 3, 2014·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Tina Tinkara PeterneljJeff S Coombes
Oct 31, 2016·Journal of Cellular Physiology·Bernardo A PetrizOctavio L Franco
Sep 10, 2009·Advanced Drug Delivery Reviews·Malcolm J Jackson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.