PMID: 9178806May 16, 1997Paper

Prediagnostic level of fatty acids in serum phospholipids: omega-3 and omega-6 fatty acids and the risk of prostate cancer

International Journal of Cancer. Journal International Du Cancer
S HarveiL J Vatten

Abstract

Ecological and case-control studies have demonstrated a positive correlation between consumption of fat and the risk of prostate cancer. Two recent human studies have focused on alpha-linolenic acid as a risk factor for prostate cancer. Animal experiments have shown that dietary omega-6 polyunsaturated fatty acids have generally stimulated tumour development, whereas omega-3 polyunsaturated fatty acids have diminished it. The aim of our study was to investigate the association between these fatty acids and the subsequent risk of prostate cancer. Blood donors to the Janus serum data bank in Norway, who later developed prostate cancer, were matched to blood donors without prostate cancer (141 matched sets); the proportional level of fatty acids measured before diagnosis in the donors' serum was examined. The risk of later prostate cancer was analysed by conditional logistic regression. Increasing risk for prostate cancer was found with increasing quartiles of palmitoleic, palmitic and alpha-linolenic acid. An inverse risk association was found with increasing levels of tetracosanoic acid, for the ratios of linoleic to alpha-linolenic acid and arachidonic to eicosapentaenoic acid. There was no clear association between the risk ef...Continue Reading

References

Apr 15, 1975·International Journal of Cancer. Journal International Du Cancer·B Armstrong, R Doll
May 11, 1991·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·W T Cave
Oct 15, 1986·Cancer·K K CarrollR Kalamegham
Oct 4, 1995·Journal of the National Cancer Institute·Y WangW D Heston
May 1, 1994·Epidemiology·L Le MarchandT Hirohata
Oct 6, 1993·Journal of the National Cancer Institute·E GiovannucciW C Willett
Feb 16, 1994·Journal of the National Cancer Institute·P H GannM J Stampfer
Nov 1, 1993·The Science of the Total Environment·E JellumH Orjasaeter
Jan 1, 1993·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·L J VattenE Jellum

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Citations

Aug 12, 2009·Lipids in Health and Disease·Breanne M Anderson, David W L Ma
Nov 27, 2009·Cancer Epidemiology·Lu YinHermann Brenner
Jan 10, 2004·The Journal of Urology·Neil FleshnerVasundara Venkateswaran
Oct 28, 2008·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Ingeborg A Brouwer
Jun 24, 2010·Journal of Photochemistry and Photobiology. B, Biology·William B Grant
Mar 6, 2003·Lipids·Andrew J SinclairDuo Li
Oct 21, 2004·The Cochrane Database of Systematic Reviews·L HooperS B J Ebrahim
Sep 15, 2005·Prostate Cancer and Prostatic Diseases·L WuermliS Gillessen
May 13, 2008·The American Journal of Clinical Nutrition·Francesca L CroweElio Riboli
Sep 30, 2008·Cancer Causes & Control : CCC·Song-Yi ParkLaurence N Kolonel
Apr 12, 2013·International Journal of Cancer. Journal International Du Cancer·Julie K BassettGraham G Giles
Jul 12, 2013·Journal of the National Cancer Institute·Theodore M BraskyAlan R Kristal
Dec 26, 2013·The American Journal of Clinical Nutrition·Liisa BybergBengt Vessby
Mar 22, 2014·Molecular and Clinical Oncology·Pinar O EserJerry T Thompson
Aug 25, 2015·BioMed Research International·Karsten H WeylandtGabriella Calviello
Apr 1, 2015·Nutrition and Cancer·Dominik D AlexanderWilliam Harris
Nov 26, 2015·Journal of the American College of Nutrition·Michael T DinwiddieRachel E Patzer
Jul 2, 2016·Integrative Cancer Therapies·Monique AucoinDugald Seely
Mar 10, 1999·Journal of the National Cancer Institute·L N KolonelR V Cooney
Jan 6, 2001·Scandinavian Journal of Urology and Nephrology. Supplementum·C C SchulmanW A Sakr
May 31, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Simon Wilkinson, Gerald W Chodak
Jun 24, 2004·The American Journal of Clinical Nutrition·Michael F LeitzmannEdward L Giovannucci
Aug 30, 2007·Cancer Causes & Control : CCC·Peter WallströmElisabet Wirfält
Nov 19, 2009·Cancer Causes & Control : CCC·Marion CarayolCyrille Delpierre
Mar 27, 2009·The American Journal of Clinical Nutrition·Joel A SimonStephen Bent
May 1, 2012·Cancer Causes & Control : CCC·Hugo Deneo-PellegriniGisele Acosta
Apr 22, 1999·Thyroid : Official Journal of the American Thyroid Association·J P BergE Glattre
Jun 9, 2001·The Prostate·L M NewcomerJ L Stanford
Feb 15, 2001·Current Opinion in Lipidology·P L Zock
Jan 27, 2005·Lipids·Nadia M Attar-BashiAndrew J Sinclair
Jun 20, 2006·Cancer Causes & Control : CCC·Daniel O KoralekMichael F Leitzmann
Jun 29, 2004·International Journal of Cancer. Journal International Du Cancer·David E LaaksonenJukka T Salonen
Apr 8, 2009·Prostate Cancer and Prostatic Diseases·D GuptaC G Lis
Apr 27, 2011·American Journal of Epidemiology·Theodore M BraskyAlan R Kristal

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