Predictability of the target stimulus for sensory-guided movement modulates early somatosensory cortical potentials

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Wynn Legon, W Richard Staines

Abstract

To investigate the role of sensory modulation in the control of sensory-guided behaviour. Specifically, we hypothesized that early somatosensory evoked potentials (SEPs) would be facilitated during performance of continuous sensory-guided movement requiring sustained attention. Median nerve SEPs were elicited via electrical stimulation and recorded from scalp electrodes while subjects performed tasks requiring continuous sensory-motor transformations. Subjects received a predictable (rhythmic amplitude modulation) or unpredictable (random amplitude modulation) amplitude varying tactile stimulus (frequency constant at 20 Hz) delivered to the tip of the index finger either alone or with the requirement to track it by modulating the isometric grip force produced by the opposite hand. Early SEP (N20-P27) amplitudes were differentially modulated during unpredictable tracking compared to sensory-motor controls. Specifically, N20 amplitudes were attenuated and P27 amplitudes were enhanced during sensory-guided tracking. Sustained attention to task-relevant sensory stimuli differentially modulates areas within primary somatosensory cortex (S1) during a continuous sensory-motor transformation. These data have implications for understand...Continue Reading

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Citations

Mar 31, 2012·Experimental Brain Research·Toshiaki WasakaRyusuke Kakigi
Sep 9, 2010·BMC Neuroscience·Wynn LegonW Richard Staines
Feb 11, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sean K MeehanLara A Boyd
Jun 9, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sean K MeehanW Richard Staines
Jan 28, 2009·Human Brain Mapping·Birgit KeiskerSpyros S Kollias
Jun 21, 2018·The European Journal of Neuroscience·Antonella MacerolloJames M Kilner
Dec 8, 2021·Experimental Gerontology·Shunsuke EbisuTomoya Ishida

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