Predicting 3-month mortality among patients hospitalized for first-ever acute ischemic stroke

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Ku-Chou ChangChia-Wei Liou

Abstract

The clinical course of patients with acute ischemic stroke tends to be unstable. Understanding the factors contributing to the progression of stroke is important for the appropriate management of patients. This study investigated the factors related to 3-month mortality at admission in patients with first-ever acute ischemic stroke. Patients with first-ever acute ischemic stroke consecutively admitted to a medical center in Taiwan within 48 hours after stroke onset were prospectively followed-up for 3 months. All deaths during this 3-month post-stroke period were analyzed. We evaluated only those characteristics that could be assessed at admission. Multivariate logistic regression analysis was used to identify the main predictors of 3-month stroke-related mortality. In the 360 enrolled patients, the inhospital mortality rate was 7.8% (28 deaths), and the 3-month mortality rate was 9.7% (35 deaths). Twenty-seven deaths (77%) were stroke-related. Risk factors for mortality at 3 months included sex (odds ratio [OR], 3.18; 95% confidence interval [CI], 1.08-9.41; p=0.036), National Institutes of Health Stroke Scale (NIHSS) at admission (per unit increase: OR, 1.17; 95% CI, 1.12-1.22; p<0.001), history of cardiac disease (OR, 2.73; ...Continue Reading

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Citations

Oct 14, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Ding DingUNKNOWN China Ischemic Stroke Registry Study (CISRS) investigators
Oct 28, 2010·Psychosomatic Medicine·Jiunn-Horng KangHerng-Ching Lin
Oct 1, 2013·Journal of the Chinese Medical Association : JCMA·Hsuei-Chen LeeTsong-Hai Lee
Feb 13, 2019·Expert Review of Pharmacoeconomics & Outcomes Research·Manik ChhabraMahendra Singh Rathore
Mar 4, 2020·International Journal of Stroke : Official Journal of the International Stroke Society·Ioannis LeventisGeorge Ntaios
Jul 17, 2021·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Irfan SahinNilufer Kale

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