Predicting and Modifying Risk for Development of Renal Failure in Boys with Posterior Urethral Valves

Current Urology Reports
Christopher J Long, Diana K Bowen

Abstract

The purpose of this review is to bring the reader up to date on the current risk factors for the development of renal deterioration in the boys with posterior urethral valves (PUV) and approaches to modify this risk. Renal bladder ultrasound (RBUS) is routinely performed in boys with PUV and recent advancements allow imaging processing that can more accurately quantify renal parenchyma and correlate this with risk for renal loss. Refinement of urine studies may improve our ability to stratify patients into renal loss categories. Use of videourodynamics (VUDS) allows refined assessment of the valve bladder to identify those who might benefit from secondary procedures and/or the addition of targeted pharmacotherapy to improve bladder emptying or dangerous storage pressures. All boys with a history of PUV are at a significant long-term risk of renal deterioration. The literature suggests that several technical advances have improved our ability to predict this risk, although there needs to be further refinement and validation before widespread use. Utilization of close follow-up, VUDS, pharmacotherapy, and bladder drainage provide the best methods to improve care to this group of patients and if more studies confirm their utility,...Continue Reading

References

Sep 1, 1997·The Journal of Urology·Y H KimK I Glassberg
Nov 12, 1998·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·D DrozdzK Schärer
Dec 18, 2001·The Journal of Urology·Stephen A KoffVenkata R Jayanthi
Feb 25, 2003·Pediatric Surgery International·Eduardo A OliveiraTiago A Fagundes
Apr 8, 2006·The Journal of Urology·Orhan ZiylanTaner Kocak
Sep 1, 2007·Seminars in Fetal & Neonatal Medicine·David LissauerMark D Kilby
Aug 19, 2008·The Journal of Urology·William DeFoorCurtis Sheldon
Oct 25, 2008·Journal of Pediatric Urology·Jian Guo WenQing Wei Wang
Oct 17, 2009·Journal of Pediatric Urology·M S AnsariRakesh Kapoor
May 13, 2011·The Journal of Urology·Osama M SarhanEl-Houssiny I Ibrahiem
Oct 20, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Michael PohlUlrike John
Oct 22, 2011·The Journal of Urology·Jukka HeikkiläSeppo Taskinen
Mar 1, 2012·Journal of Pediatric Urology·Tayfun OktarOrhan Ziylan
Aug 30, 2012·Nature Methods·Caroline A SchneiderKevin W Eliceiri
Aug 21, 2013·Lancet·Rachel K MorrisUNKNOWN Percutaneous vesicoamniotic shunting in Lower Urinary Tract Obstruction (PLUTO) Collaborative Group
Dec 7, 2013·Clinical Journal of the American Society of Nephrology : CJASN·Jose E PulidoGregory E Tasian
Jan 28, 2014·Korean journal of urology·Mehdi ShiraziAbbasali Khakbaz
Feb 25, 2014·Journal of Pediatric Urology·Ibrahim MokhlessMohamed E Youssif
Apr 13, 2015·Journal of Pediatric Urology·Sorena KeihaniAbdol-Mohammad Kajbafzadeh
Aug 22, 2015·Journal of Pediatric Urology·R ColemanK Parashar
Oct 7, 2015·Journal of Pediatric Urology·L I Smith-HarrisonSean T Corbett
Mar 2, 2016·The Journal of Urology·Katherine FischerGregory E Tasian
Aug 30, 2016·Journal of Pediatric Urology·Marie-Klaire Farrugia
Feb 25, 2017·Current Urology Reports·Charles W ConcodoraBrian A VanderBrink

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Citations

May 30, 2019·Frontiers in Pediatrics·Chryso P KatsoufisCarolyn L Abitbol

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