Predicting in-hospital death in patients with type B acute aortic dissection

Medicine
Jing ZhangZiping Cheng

Abstract

The outcome of patients with acute type B aortic dissection (BAAD) is largely dictated by whether or not the case is "complicated." The purpose of this study was to investigate the risk factors leading to in-hospital death among patients with BAAD and then to develop a predictive model to estimate individual risk of in-hospital death.A total of 188 patients with BAAD were enrolled. Risk factors for in-hospital death were investigated with univariate and multivariable logistic regression analysis. Significant risk factors were used to develop a predictive model.The in-hospital mortality rate was 9% (17 of 188 patients). Univariate analysis revealed 7 risk factors to be statistically significant predictors of in-hospital death (P < .1). In multivariable analysis, the following variables at admission were independently associated with increased in-hospital mortality: hypotension (odds ratio [OR], 4.85; 95% confidence interval [CI], 1.12-18.90; P = .04), ischemic complications (OR, 8.24; 95% CI, 1.25-33.85; P < .001), renal dysfunction (OR, 12.32; 95% CI, 10.63-76.66; P < .001), and neutrophil percentage ≥80% (OR, 5.76; 95% CI, 2.58-12.56; P = .03). Based on these multivariable results, a reliable and simple prediction model was de...Continue Reading

References

Sep 15, 2010·Circulation·Santi TrimarchiUNKNOWN International Registry of Acute Aortic Dissection (IRAD) Investigators
Aug 4, 2011·European Heart Journal·Christoph A Nienaber, Janet T Powell
May 12, 2012·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·J BrunkwallP Taylor
Feb 23, 2013·JACC. Cardiovascular Interventions·Yong-Lin QinGao-Jun Teng
Mar 13, 2013·The Annals of Thoracic Surgery·D Andrew WilkinsonG Michael Deeb
Aug 8, 2013·Circulation. Cardiovascular Interventions·Christoph A NienaberUNKNOWN INSTEAD-XL trial
Dec 4, 2014·Heart, Lung & Circulation·Jing ZhangAiling Wang
Jul 1, 2013·Aorta : Official Journal of the Aortic Institute at Yale-New Haven Hospital·Jip L TolenaarSanti Trimarchi

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Methods Mentioned

BETA
dissection

Software Mentioned

SPSS

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